Evidence map›Paper›PMID 33823185›Full record

ArticleEuropean journal of pharmacology2021

Virtual high throughput screening: Potential inhibitors for SARS-CoV-2 PL

Dhananjay Jade, Selvaraj Ayyamperumal, Vyshnavi Tallapaneni, Chandrasekar Moola Joghee Nanjan, Sagar Barge, Surender Mohan, Moola Joghee Nanjan

Open access · greenAbstract read
In one paragraph

Article in European journal of pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 43 citations in OpenAlex.

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  8. A review onExploration of targeted anti-tumor therapy · 2023
    Review
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  12. Article
  13. Article
  14. Therapeutics for COVID-19 and post COVID-19 complications: An update.Current research in pharmacology and drug discovery · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. An overview of potential inhibitors targeting non-structural proteins 3 (PLComputational and structural biotechnology journal · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dhananjay JadeDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, 643001, Tamilnadu, India.
Selvaraj AyyamperumalDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, 643001, Tamilnadu, India.
Vyshnavi TallapaneniDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, 643001, Tamilnadu, India.
Chandrasekar Moola Joghee NanjanDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, 643001, Tamilnadu, India. Electronic address: ncsekar@jssuni.edu.in.
Sagar BargeBiochemistry and Drug Discovery Lab, Institute of Advanced Study in Science and Technology, Paschim Boragaon, Guwahati, 35, Assam, India.
Surender MohanSchool of Biotechnology, Laboratory of Molecular Biology and Genetic Engineering, JNU, New Delhi, 110067 India.
Moola Joghee NanjanJSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, 643001, Tamilnadu, India. Electronic address: mjnanjan@gmail.com.
JSS Academy of Higher Education and Research · INInstitute of Advanced Study in Science and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pandemic, COVID-19, has spread worldwide and affected millions of people. There is an urgent need, therefore, to find a proper treatment for the novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the causative agent. This paper focuses on identifying inhibitors that target SARS-CoV-2 proteases, PL

Indexed as

COVID-19 Drug TreatmentAntiviral AgentsCatalytic DomainDatabases, FactualDrug RepositioningHigh-Throughput Screening AssaysHumansHydrogen BondingHydrophobic and Hydrophilic InteractionsModels, MolecularMolecular Docking SimulationMolecular Dynamics SimulationProtease InhibitorsSaltsSARS-CoV-2Viral Nonstructural ProteinsAntiviral AgentsProtease InhibitorsSaltsViral Nonstructural Proteins3CL(PRO)COVID-19Drug repositioningPL(PRO)SARS-CoV-2

Identifiers

PMID33823185
PMCPMC8018918
OpenAlexW3141439967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.