Evidence map›Paper›PMID 33822982›Full record

ArticleJournal of animal science2021

Effects of vaccination against brucellosis and clostridia on the intake, performance, feeding behavior, blood parameters, and immune responses of dairy heifers calves.

Hilton C Diniz Neto, Mayara C Lombardi, Mariana M Campos, Andrey P Lage, Rodrigo O S Silva, Elaine Maria Seles Dorneles, Camila Flávia A Lage, Wanessa A Carvalho, Fernanda S Machado, Luiz Gustavo R Pereira and 8 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of animal science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Hilton C Diniz NetoDepartamento de Zootecnia, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 30161-970, Brazil.
Mayara C LombardiDepartamento de Zootecnia, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 30161-970, Brazil.
Mariana M CamposEmpresa Brasileira de Pesquisa Agropecuária - Embrapa Gado de Leite, Juiz de Fora, Minas Gerais, 36038-330, Brazil.
Andrey P LageDepartamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, 30161-970, Brazil.
Rodrigo O S SilvaDepartamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, 30161-970, Brazil.
Elaine Maria Seles DornelesDepartamento de Medicina Veterinária, Universidade Federal de Lavras, Lavras, Minas Gerais, 30161-970, Brazil.
Camila Flávia A LageDepartamento de Zootecnia, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 30161-970, Brazil.
Wanessa A CarvalhoEmpresa Brasileira de Pesquisa Agropecuária - Embrapa Gado de Leite, Juiz de Fora, Minas Gerais, 36038-330, Brazil.
Fernanda S MachadoEmpresa Brasileira de Pesquisa Agropecuária - Embrapa Gado de Leite, Juiz de Fora, Minas Gerais, 36038-330, Brazil.
Luiz Gustavo R PereiraEmpresa Brasileira de Pesquisa Agropecuária - Embrapa Gado de Leite, Juiz de Fora, Minas Gerais, 36038-330, Brazil.
Thierry R TomichEmpresa Brasileira de Pesquisa Agropecuária - Embrapa Gado de Leite, Juiz de Fora, Minas Gerais, 36038-330, Brazil.
Carolina P RamosDepartamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, 30161-970, Brazil.
Ronnie A AssisDepartamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, 30161-970, Brazil.
Francisco Carlos F LobatoDepartamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, 30161-970, Brazil.
Jordana A SantanaDepartamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, 30161-970, Brazil.
Ethiene Luiza S SantosDepartamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, 30161-970, Brazil.
Rafaella S AndradeDepartamento de Medicina Veterinária, Universidade Federal de Lavras, Lavras, Minas Gerais, 30161-970, Brazil.
Sandra G CoelhoDepartamento de Zootecnia, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 30161-970, Brazil.
Universidade Federal de Minas Gerais · BRBrazilian Agricultural Research Corporation · BRUniversidade Federal de Lavras · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to identify possible effects of different vaccination strategies (concomitantly or not) against brucellosis and clostridia on intake, performance, feeding behavior, blood parameters, and immune responses of dairy heifers calves. Fifty heifers calves were enrolled [38 Gyr (Zebu, Bos taurus indicus) and 12 5/8 Holstein × Gyr]. At 120 d of age, animals were randomly distributed among 3 groups: B (n = 18), vaccinated against brucellosis; C (n = 14), vaccinated against clostridia and CB (n = 18), vaccinated concomitantly for both. Rectal and thermographic temperatures were evaluated on days -1, 0, 1, 2, 3, 5, 7,10, 14, and 28 relatives to the vaccination day. Feed and water intake, body weight (BW), and feeding behavior were monitored daily by an electronic feeding system. Blood was sampled on days 0, 3, 7, 14, and 28, relative to the vaccination day for determination of glucose and β -hydroxybutyrate (BHBA) concentrations. Blood sampled on day 0 (prevaccination) and on days 28 and 42 were used to evaluate the immune response against Brucella abortus and clostridia. There was an increase in rectal temperature between the first and the third day postvaccination in the 3 groups. The thermography revealed an increase of local temperature for 7 d on groups B and CB. Group C had increased local temperature for a longer period, lasting for up to 14 d. Dry mater intake was reduced for groups B and CB, but no alteration was observed for group C. No alterations regarding initial BW, final BW, average daily weight gain, and feed efficiency were observed. No differences were observed for the 3 vaccination groups for blood parameters throughout the evaluation period. The concomitant vaccination against brucellosis and clostridia led to lower neutralizing antibody titers against epsilon toxin of Clostridium perfringens and botulinum toxin type C of C. botulinum (C > CB > B). When cellular proliferation assay and serological tests to B. abortus were evaluated, no differences were observed between groups B and CB. The present results indicate that the concomitant vaccination against brucellosis and clostridia has no relevant impact on the intake, performance, and feeding behavior of dairy calves. However, the concomitant vaccination of vaccines against these 2 pathogens impacts animal immunity against clostridial infections.

Indexed as

BrucellosisCattle DiseasesAnimal FeedAnimalsBody WeightCattleFeeding BehaviorFemaleImmunityVaccinationBrucella abortusClostridium botulinumClostridium perfringensintake

Identifiers

PMID33822982
PMCPMC8139319
OpenAlexW3145080165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.