Evidence map›Paper›PMID 33822807›Full record

Trial reportPloS one2021

Magnitude and associated factors of poor medication adherence among diabetic and hypertensive patients visiting public health facilities in Ethiopia during the COVID-19 pandemic.

Tariku Shimels, Rodas Asrat Kassu, Gelila Bogale, Mahteme Bekele, Melsew Getnet, Abrham Getachew, Zewdneh Shewamene, Mebratu Abraha

Open access · goldAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Impact of COVID-19 Pandemic on Adherence to Chronic Therapies: A Systematic Review.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tariku ShimelsResearch Directorate, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.ORCID 0000-0001-5212-7597
Rodas Asrat KassuDepartment of Neurology, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Gelila BogaleUnited Vision Medical Services, Addis Ababa, Ethiopia.ORCID 0000-0003-3444-5801
Mahteme BekeleResearch Directorate, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Melsew GetnetResearch Directorate, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Abrham GetachewResearch Directorate, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Zewdneh ShewameneEthiopian Health Insurance Agency, Addis Ababa, Ethiopia.
Mebratu AbrahaResearch Directorate, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
St. Paul's Hospital Millennium Medical College · ETGovernment of Ethiopia · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to assess the magnitude and associated factors of poor medication adherence among diabetic and hypertensive patients visiting public health facilities in Addis Ababa, Ethiopia during the COVID-19 pandemic.

methodsA multi-site cross-sectional design was conducted from 1st through 30th of August 2020 at public health facilities of the study area. Adult outpatients with T2DM and hypertension visiting hospitals and health centers were included in the study. A proportion to size allocation method was used to determine the required sample size per facility. Data was collected using the 8-item Morisky medication adherence scale. Descriptive statistics and binary logistic regression were used to analyze data. A 95% confidence interval and p≤0.05 statistical significance was considered to determine factors associated with poor medication adherence.

resultsA total of 409 patients were included in the present study. About 57% of the patients reported that the COVID-19 pandemic has posed negative impacts on either of their follow-up visits, availability of medications, or affordability of prices. And, 21% have reported that they have been affected in all aspects. The overall magnitude of poor medication adherence was 72%. Patients with extreme poverty were more likely to have good medication adherence (AOR: 0.59; 95%C.I: 0.36-0.97), whereas attendance to a health center (AOR: 1.71; 95%C.I: 1.02-2.85), presence of comorbidity (AOR: 2.05; 95%C.I: 1.13-3.71), and current substance use history (AOR: 11.57; 95%C.I: 1.52-88.05) predicted high odds of poor adherence.

conclusionOver a three-fourth of the patients, in the study setting, have poor adherence to their anti-diabetic and antihypertensive medications. Health facility type, income level, comorbidity, and current substance use history showed a statistically significant association with poor adherence to medication. Stakeholders should set alternative strategies as perceived impacts of the COVID-19 pandemic on medication adherence are high in the study area.

Indexed as

COVID-19COVID-19 Drug TreatmentDiabetes Mellitus, Type 2HypertensionMedication AdherencePandemicsAdultAntihypertensive AgentsCross-Sectional StudiesEthiopiaFemaleFollow-Up StudiesHumansHypoglycemic AgentsMaleMiddle AgedAntihypertensive AgentsHypoglycemic Agents

Identifiers

PMID33822807
PMCPMC8023457
OpenAlexW3141653433

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.