Evidence map›Paper›PMID 33822653›Full record

ArticleJCO clinical cancer informatics2021

Natural Language Processing to Identify Cancer Treatments With Electronic Medical Records.

Jiaming Zeng, Imon Banerjee, A Solomon Henry, Douglas J Wood, Ross D Shachter, Michael F Gensheimer, Daniel L Rubin

Open access · greenAbstract read
In one paragraph

Article in JCO clinical cancer informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Developing the multidisciplinary and multispecialty workforce and the systems needed to sustain high-quality care from diagnosis through long-term survivorship.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jiaming ZengDepartment of Management Science and Engineering, Huang Engineering Center, Stanford, CA.ORCID 0000-0003-2927-5916
Imon BanerjeeDepartment of Biomedical Informatics, Department of Radiology, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-3327-8004
A Solomon HenryResearch Informatics Center, Stanford University, Stanford, CA.ORCID 0000-0003-1591-1897
Douglas J WoodResearch Informatics Center, Stanford University, Stanford, CA.
Ross D ShachterDepartment of Management Science and Engineering, Stanford University School of Engineering, Stanford, CA.ORCID 0000-0003-4693-4434
Michael F GensheimerDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, CA.ORCID 0000-0002-4897-3843
Daniel L RubinDepartment of Biomedical Data Science, Radiology, and Medicine (Biomedical Informatics), Stanford University School of Medicine, Stanford, CA.ORCID 0000-0002-4332-9696
Stanford University · USEmory University · US

Funding

Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI Vittorio Sebastiano · 2007 to 2026
$71.4M
NCI NIH HHS P30 CA124435
6 · The paper itself

Abstract

purposeKnowing the treatments administered to patients with cancer is important for treatment planning and correlating treatment patterns with outcomes for personalized medicine study. However, existing methods to identify treatments are often lacking. We develop a natural language processing approach with structured electronic medical records and unstructured clinical notes to identify the initial treatment administered to patients with cancer.

methodsWe used a total number of 4,412 patients with 483,782 clinical notes from the Stanford Cancer Institute Research Database containing patients with nonmetastatic prostate, oropharynx, and esophagus cancer. We trained treatment identification models for each cancer type separately and compared performance of using only structured, only unstructured (

resultsFor prostate cancer, we achieved an f1-score of 0.99 (95% CI, 0.97 to 1.00) for radiation and 1.00 (95% CI, 0.99 to 1.00) for surgery using

conclusionOur results show that treatment identification using free-text clinical notes greatly improves upon the performance using billing codes and simple structured data. The approach can be used for treatment cohort identification and adapted for longitudinal cancer treatment identification.

Indexed as

Natural Language ProcessingNeoplasmsCohort StudiesElectronic Health RecordsHumansLogistic ModelsMachine LearningMale

Identifiers

PMID33822653
PMCPMC12754722
OpenAlexW3145444482

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.