ArticleEnvironmental health perspectives2021
Fluoride in Drinking Water, Diet, and Urine in Relation to Bone Mineral Density and Fracture Incidence in Postmenopausal Women.
Article in Environmental health perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- The association of fluoride exposure with bone density and fracture risk: a dose-response meta-analysis.Environmental health : a global access science source · 2025Pooled it
- SIMPLER: the Swedish infrastructure for medical population-based life-course and environmental research.European journal of epidemiology · 2026Article
- Identifying dietary sources and patterns of exposure to toxic metals and other trace elements in Swedish toddlers and young children.Journal of exposure science & environmental epidemiology · 2026Article
- Article
- Per- and polyfluoroalkyl substances and adolescent bone mineral density: assessing periods of susceptibility.Journal of the Endocrine Society · 2026Article
- Maternal serum polybrominated diphenyl ether concentrations during pregnancy and adolescent bone mineral density at age 12 years.International journal of hygiene and environmental health · 2026Article
- Radiographic sclerosis with intraoperative fragile bone in skeletal fluorosis: a case report.Frontiers in surgery · 2026Article
- Hydration Meets Regulation: Insights into Bicarbonate Mineral Water and Acid-Base Balance.Nutrients · 2025Review
- Updated consumer risk assessment of fluoride in food and drinking water including the contribution from other sources of oral exposure.EFSA journal. European Food Safety Authority · 2025Article
- Occupational Exposure to Disinfectants and Risk of Incident Cardiovascular Disease among US Nurses: The Nurses' Health Study II.Environmental health perspectives · 2025Article
- Sodium fluoride accelerates apoptosis, oxidative stress and matrix degradation of condylar chondrocytes by upregulating MMP-13 and RANKL.American journal of translational research · 2025Article
- Associations between Dietary Patterns, Fluoride Intake and Excretion in Women Exposed to Fluoridated Salt: A Preliminary Study.Nutrients · 2024Article
- Association of fluoride exposure with disease burden and neurodevelopment outcomes in children in South Korea.World journal of pediatrics : WJP · 2024Article
- The Association between Fluoride and Bone Mineral Density in US Children and Adolescents: A Pilot Study.Nutrients · 2024Article
- Community Water Fluoridation and Rate of Pediatric Fractures.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2023Article
- The Role of Trace Elements and Minerals in Osteoporosis: A Review of Epidemiological and Laboratory Findings.Biomolecules · 2023Review
- Associations of urinary metabolite concentrations of phthalates and phthalate replacements with body composition from mid-childhood to early adolescence.Environmental research · 2023Article
- Relationships between dental fluorosis and fluoride concentrations in bottled water and groundwater in low-income children in Mexico.Frontiers in oral health · 2023Article
- Fluoride - a scoping review for Nordic Nutrition Recommendations 2023.Food & nutrition research · 2023Article
- Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough randomized controlled trials (RCTs) have demonstrated that high fluoride increases bone mineral density (BMD) and skeletal fragility, observational studies of low-dose chronic exposure through drinking water (
objectiveWe assessed associations of fluoride in urine, and intake via diet and drinking water, with BMD and fracture incidence in postmenopausal women exposed to drinking water fluoride
methodsData were from participants in the Swedish Mammography Cohort-Clinical, a population-based prospective cohort study. At baseline (2004-2009), fluoride exposure was assessed based on urine concentrations (
resultsAt baseline, mean urine fluoride was DISCUSSION: In this cohort of postmenopausal women, the risk of fractures was increased in association with two separate indicators of fluoride exposure. Our findings are consistent with RCTs and suggest that high consumption of drinking water with a fluoride concentration of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.