Evidence map›Paper›PMID 33822641›Full record

ReviewJCO global oncology2021

Challenge of Incorporating New Drugs for Breast Cancer in Brazil: A Proposed Framework for Improving Access to Innovative Therapies.

Carlos Barrios, Ruffo Freitas-Junior, Sandro Martins, Jose Bines, Maria Del Pilar Estevez-Diz, Maira Caleffi

Open access · goldAbstract readReview
In one paragraph

Review in JCO global oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 4 countries.

Carlos BarriosGrupo Oncoclínicas, Latin American Cooperative Oncology Group (LACOG), Porto Alegre, Brazil.ORCID 0000-0001-6021-667X
Ruffo Freitas-JuniorCORA, Advanced Center for Diagnosis of Breast Diseases, Federal University of Goias, Goiânia, Brazil.ORCID 0000-0003-4145-8598
Sandro MartinsMedical Oncology Unit, University Hospital of Brasília/EBSERH, Brasília, Brazil.ORCID 0000-0002-5500-8734
Jose BinesClínica São Vicente, Rio de Janeiro, Brazil.ORCID 0000-0003-2465-8854
Maria Del Pilar Estevez-DizInstituto do Câncer do Estado de São Paulo/Faculdade de Medicina da Universidade de São Paulo, Onco Star Rede D'Or, São Paulo, Brazil.
Maira CaleffiHospital Moinhos de Vento, Femama, Porto Alegre, Brazil.
Roche (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objective of this review is to address the barriers limiting access to treatment of advanced metastatic breast cancer (mBC) in Brazil, specifically for patients in the public health care system, arguably those with the least access to innovation. MATERIALS AND

methodsA selected panel of Brazilian experts in BC were provided with a series of relevant questions to address in a multiday conference. During the conference, responses were discussed and edited by the entire group through numerous drafts and rounds of discussion until a consensus was achieved.

resultsThe authors propose specific and realistic recommendations for implementing access to new drugs in cancer care in Brazil. Moreover, in creating these recommendations and framework, the authors strive to address the most important barriers and impediments for technology incorporation. A feasible and specific multidisciplinary process is proposed, which is based on the collective participation of all involved stakeholders.

conclusionGiven the current benefits and likely future developments, there is a great need to expand treatments for mBC not only in Brazil but also in most other countries in the world where access issues remain an unresolved demand. Adapting the current framework is essential for accomplishing this goal. The recommendations in this review can serve as a framework for adoption of new technologies in countries with limited resources.

Indexed as

Breast NeoplasmsPharmaceutical PreparationsBrazilConsensusFemaleHumansTherapies, InvestigationalPharmaceutical Preparations

Identifiers

PMID33822641
PMCPMC8081546
OpenAlexW3144004986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.