Evidence map›Paper›PMID 33822472›Full record

ArticleDiabetes, obesity & metabolism2021

Longevity of the novel ConvaTec infusion set with Lantern technology.

Rayhan A Lal, Liana Hsu, Jian Zhang, Pernelle K Schøndorff, Matthias Heschel, Bruce Buckingham

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Diabetes, obesity & metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03819634 (Longevity of Multi-Slitted Catheter, the Convatec Inset II With Lantern Technology), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03819634 nacompletednot on this map

Longevity of Multi-Slitted Catheter, the Convatec Inset II With Lantern Technology

TypeinterventionalSponsorStanford UniversityRan2019 to 2019Enrolled24ConditionsInsulin Dependent Diabetes Mellitus 1ArmsInset II with Lantern Technology
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Automated Insulin Delivery for Type 1 Diabetes: Present and Future.Diabetes spectrum : a publication of the American Diabetes Association · 2025
    Article
  4. Article
  5. Insulin Delivery Hardware: Pumps and Pens.Diabetes technology & therapeutics · 2024
    Article
  6. Development of the Extended Infusion Set and Its Mechanism of Action.Journal of diabetes science and technology · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Advances in Insulin Pump Infusion Sets Symposium Report.Journal of diabetes science and technology · 2021
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Rayhan A LalDivision of Endocrinology, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-8055-944X
Liana HsuDivision of Endocrinology, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA.
Jian ZhangDivision of Endocrinology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Pernelle K SchøndorffConvaTec, Copenhagen, Denmark.
Matthias HeschelConvaTec, Copenhagen, Denmark.
Bruce BuckinghamDivision of Endocrinology, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA.
ConvaTec (United Kingdom) · GBStanford Medicine · USStanford University · US

Funding

Stanford Center for Clinical & Translational Education and Research (Spectrum)UL1TR003142 · NCATS · STANFORD UNIVERSITY · PI O'HARA, RUTH M · 2019 to 2023
$45.0M
Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
Stanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI Seung K Kim · 2017 to 2026
$19.5M
Diabetes, Endocrinology and Metabolism Training GrantT32DK007217 · NIDDK · STANFORD UNIVERSITY · PI Justin Pierce Annes, David Matthew Maahs · 1987 to 2026
$7.2M
Network Control of Diabetes: Aligning Artificial Pancreas Design with PhysiologyDP3DK101055 · NIDDK · UNIVERSITY OF VIRGINIA · PI KOVATCHEV, BORIS P · 2013 to 2013
$3.4M
Using a Closed-Loop System Plus Behavioral Supports in Preschoolers with DiabetesDP3DK104059 · NIDDK · STANFORD UNIVERSITY · PI BUCKINGHAM, BRUCE A, DIMEGLIO, LINDA A · 2014 to 2014
$2.1M
Training Research Leaders in Type 1 DiabetesK12DK122550 · NIDDK · STANFORD UNIVERSITY · PI MAAHS, DAVID MATTHEW · 2019 to 2023
$2.1M
The Optimal Pathway to Implanted Autonomous Insulin DeliveryK23DK122017 · NIDDK · STANFORD UNIVERSITY · PI LAL, RAYHAN · 2020 to 2024
$958k
NCATS NIH HHS UL1 TR001085NCATS NIH HHS UL1 TR003142NIDDK NIH HHS DP3 DK101055NIDDK NIH HHS DP3 DK104059NIDDK NIH HHS K12 DK122550NIDDK NIH HHS K23 DK122017NIDDK NIH HHS P30 DK116074NIDDK NIH HHS T32 DK007217
6 · The paper itself

Abstract

Current insulin infusion sets are approved for only 2-3 days. The novel ConvaTec infusion set with Lantern technology is designed to extend infusion set wear time. The goal of this pilot study was to evaluate the duration of wear for this set. This was a pilot safety study in adults with type 1 diabetes using tethered insulin pumps. Participants inserted the set and wore it for 10 days or until failure. Among 24 participants, two were excluded. Forty-five per cent of the sets lasted 10 days. Median wear time was 9.1 (7.1, 10.0) days. Among 12 premature failures, six (50%) involved adhesive failures, four (33%) hyperglycaemia unresponsive to correction, one (8%) hyperglycaemia with ketones and one (8%) infection. Average CGM glucose per day of infusion set wear showed a statistically significant increase over time, while total daily insulin over the same period did not change. In this pilot study, the duration of wear for the novel infusion set exceeded previously reported commercial sets (P < .001). This extended wear technology may eventually allow for a combined glucose sensor and infusion set.

Indexed as

Blood Glucose Self-MonitoringDiabetes Mellitus, Type 1AdultBlood GlucoseHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsPilot ProjectsTechnologyBlood GlucoseHypoglycemic AgentsInsulinCSIIinsulin pump therapyinsulin therapytype 1 diabetes

Identifiers

PMID33822472
PMCPMC8720264
OpenAlexW3144920652

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.