Evidence map›Paper›PMID 33821786›Full record

ArticleeLife2021

Discovery and characterization of a novel family of prokaryotic nanocompartments involved in sulfur metabolism.

Robert J Nichols, Benjamin LaFrance, Naiya R Phillips, Devon R Radford, Luke M Oltrogge, Luis E Valentin-Alvarado, Amanda J Bischoff, Eva Nogales, David F Savage

Abstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Chemical reviews · 2026
    Review
  5. Review
  6. Article
  7. Characterization of Iron Oxide Nanoparticles Inside theNanomaterials (Basel, Switzerland) · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Encapsulins: catalysis inside a shell.Current opinion in microbiology · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Viruses · 2025
    Article
  16. Article
  17. The Structural Diversity of Encapsulin Protein Shells.Chembiochem : a European journal of chemical biology · 2024
    Review
  18. Bacterial Organelles in Iron Physiology.Molecular microbiology · 2024
    Review
  19. Structural Characterization ofMicroorganisms · 2024
    Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Robert J Nichols *Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0002-8476-0554
Benjamin LaFrance *Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
Naiya R PhillipsDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0003-1836-5182
Devon R RadfordDepartment of Molecular Genetics, University of Toronto, Toronto, Canada.
Luke M OltroggeDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0001-5716-9980
Luis E Valentin-AlvaradoDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, United States.
Amanda J BischoffDepartment of Chemistry, University of California Berkeley, Berkeley, United States.
Eva NogalesDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0001-9816-3681
David F SavageDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0003-0042-2257

Funding

TUBULIN STRUCTURE BY ELECTRON CRYSTALLOGRAPHYP01GM051487 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI DOUDNA, JENNIFER A · 1994 to 2018
$27.6M
Howard Hughes Medical InstituteNational Science Foundation GRFP-1106400NIGMS NIH HHS P01 GM051487U.S. Department of Energy DE-SC00016240
6 · The paper itself

Abstract

Prokaryotic nanocompartments, also known as encapsulins, are a recently discovered proteinaceous organelle-like compartment in prokaryotes that compartmentalize cargo enzymes. While initial studies have begun to elucidate the structure and physiological roles of encapsulins, bioinformatic evidence suggests that a great diversity of encapsulin nanocompartments remains unexplored. Here, we describe a novel encapsulin in the freshwater cyanobacterium

Indexed as

Bacterial ProteinsCryoelectron MicroscopySulfurSynechococcusBacterial ProteinsSulfurcryo-EME. coliencapsulininfectious diseasemicrobiologymolecular biophysicsnanocompartmentprokaryotic organellestructural biologysulfur starvationSynechococcus elongatus

Identifiers

PMID33821786
PMCPMC8049743

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.