Evidence map›Paper›PMID 33821440›Full record

ReviewMolecular biology reports2021

Unsaturated fatty acids as a co-therapeutic agents in cancer treatment.

Zahra Asefy, Asghar Tanomand, Sirus Hoseinnejhad, Zaker Ceferov, Ebrahim Abbasi Oshaghi, Mohsen Rashidi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The Benthic DinoflagellateMarine drugs · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Obesity and lipid metabolism in the development of osteoporosis (Review).International journal of molecular medicine · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. The Role and Mechanism ofMolecules (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Zahra AsefySchool of Nursing and Allied Medical Sciences Maragheh University of Medical Sciences, Maragheh, Iran. zasefy@gmail.com.ORCID http://orcid.org/0000-0002-3176-4105
Asghar TanomandSchool of Nursing and Allied Medical Sciences Maragheh University of Medical Sciences, Maragheh, Iran.
Sirus HoseinnejhadSchool of Nursing and Allied Medical Sciences Maragheh University of Medical Sciences, Maragheh, Iran.
Zaker CeferovBaku State University, Baku, Azerbaijan.
Ebrahim Abbasi OshaghiDepartment of Clinical Biochemistry, School of Medicine Hamadan University of Medical Sciences, Hamadan, Iran.
Mohsen RashidiDepartment of Physiology and Pharmacology, School of Medicine The Health of Plant and Livestock Products Research Center Mazandaran University of Medical Sciences, Mazandaran, Iran.
University of Maragheh · IRBaku State University · AZHamedan University of Medical Sciences · IRMazandaran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemotherapy is standard treatments for many malignancies. However, in most cases, this method is not able to induce apoptosis and in many cases, with cancer recurrence, leads to patient death. There are several procedure to control and suppress malignant cells, but among these methods, administration of ɷ-3 fatty acids and ɷ-6 fatty due to their destructive effects on cancer cells is more prominent. Many clinical studies have shown beneficial effects of ɷ-3 and ɷ-6 fatty acids in cardiovascular disorders, asthma, rheumatoid arthritis, osteoporosis and in most cancers such as colon, breast, prostate and other malignancies. Studies showed that polyunsaturated fatty acids (PUFAs) have a toxic effect on cancer cells. However, the exact mechanism of how ɷ- fatty acids affect cancer cells is still unknown. In this review alternative issues of malignancies co-treatments agents such as PUFAs have been studied. Also, the latest known PUFAs mechanisms on malignancies have been described.

Indexed as

AnimalsAntineoplastic AgentsFatty Acids, UnsaturatedHumansImmune SystemNeoplasmsAntineoplastic AgentsFatty Acids, UnsaturatedCancerMolecular pathwaysPolyunsaturated fatty acids (PUFAs)

Identifiers

PMID33821440
OpenAlexW3152273547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.