Evidence map›Paper›PMID 33821439›Full record

Trial reportSleep & breathing = Schlaf & Atmung2022

Clinical safety and hemodynamic, cardiac autonomic and inflammatory responses to a single session of inspiratory muscle training in obstructive sleep apnea.

Sílvia Thamilis Barbosa Pessoa Ferreira, Maria do Socorro Brasileiro-Santos, Juliana Baptista Teixeira, Michelle Christiane da Silva Rabello, Virgínia Maria Barros de Lorena, Breno Quintella Farah, Thayse Neves Santos Silva, Anna Myrna Jaguaribe de Lima

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sílvia Thamilis Barbosa Pessoa FerreiraPost Graduate Program of Physical Therapy, Federal University of Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Cidade Universitária, Recife, PE, CEP: 50670-901, Brazil.
Maria do Socorro Brasileiro-SantosDepartment of Physical Education, Federal University of Paraíba (UFPB), Cidade Universitária, s/n - Castelo Branco III, João Pessoa, PB, CEP: 58051-900, Brazil.
Juliana Baptista TeixeiraPost Graduate Program of Physical Therapy, Federal University of Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Cidade Universitária, Recife, PE, CEP: 50670-901, Brazil.
Michelle Christiane da Silva RabelloDepartment de Immunology, Aggeu Magalhães Institute, Recife, PE, CEP: 50670-420, Brazil.
Virgínia Maria Barros de LorenaDepartment de Immunology, Aggeu Magalhães Institute, Recife, PE, CEP: 50670-420, Brazil.
Breno Quintella FarahDepartment of Physical Education, Federal Rural University of Pernambuco (UFRPE), Rua Manoel de Medeiros, s/n, Dois Irmãos, Recife, PE, CEP: 52171-900, Brazil.
Thayse Neves Santos SilvaDepartment of Rehabilitation, Hospital Otávio de Freitas (HOF), Rua Aprígio Guimarães, s/n, Tejipió, Recife, PE, CEP: 50920-460, Brazil.
Anna Myrna Jaguaribe de LimaPost Graduate Program of Physical Therapy, Federal University of Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Cidade Universitária, Recife, PE, CEP: 50670-901, Brazil. anna.myrna@ufrpe.br.
Universidade Federal de Pernambuco · BRUniversidade Federal Rural de Pernambuco · BRUniversidade Federal da Paraíba · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine clinical safety and cardiovascular, cardiac autonomic and inflammatory responses to a single session of inspiratory muscle training (IMT) in obstructive sleep apnea (OSA) subjects.

methodsIn a randomized controlled trial individuals of both sexes, aged between 30 and 70 years old with diagnosis of moderate to severe OSA were enrolled. Volunteers with OSA (n = 40) performed an IMT session with three sets of 30 repetitions with a 1-min interval between them. The IMT group (n = 20) used a load of 70% of the maximum inspiratory pressure (MIP), and the placebo group (n = 20) performed the IMT without load. Measurements of systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), heart rate variability (HRV), and inflammatory markers were performed pre, post-immediate and 1 h after the IMT session.

resultsNo differences were shown in SBP, DBP, HRV, or inflammatory markers at any of the intervals analyzed. However, HR in the IMT group was lower ​​1 h after the IMT session compared to the pre-session values ​​(p = 0002). HR was higher in the placebo group when comparing pre × post-immediate (p < 0.001). HR decreased after the first hour in relation to the pre (p < 0.001) and post-immediate (p < 0.001) values.

conclusionIMT sessions promote discreet hemodynamic, cardiac autonomic and inflammatory responses. Therefore, IMT is considered clinically safe and can be performed at home, guided but unsupervised, with lower cost and greater adherence to exercise program for subjects with OSA.

Indexed as

AdultAgedAutonomic Nervous SystemBreathing ExercisesCardiovascular DiseasesExerciseFemaleHumansMaleMiddle AgedResistance TrainingRespiratory MusclesSleep Apnea, ObstructiveTreatment OutcomeBreathing exercisesCardiovascular systemHeart rate variabilityInflammationPatient safetySleep apnea

Identifiers

PMID33821439
OpenAlexW3146442044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.