Evidence map›Paper›PMID 33821434›Full record

ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2021

Impact of a Mandatory Prescription Drug Monitoring Program Check on Emergency Department Opioid Prescribing Rates.

C James Watson, Michael Ganetsky, Ryan C Burke, Yotam Dizitzer, Evan L Leventhal, Katherine L Boyle

Abstract read
In one paragraph

Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

C James WatsonDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, 1 Deaconess Road, 2nd Floor, Boston, MA, 02215, USA. cjwatson@bidmc.harvard.edu.ORCID 0000-0002-1003-5798
Michael GanetskyDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, 1 Deaconess Road, 2nd Floor, Boston, MA, 02215, USA.
Ryan C BurkeDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, 1 Deaconess Road, 2nd Floor, Boston, MA, 02215, USA.
Yotam DizitzerClinical Research Center, Soroka University Medical Center, Beer-Sheba, Israel.
Evan L LeventhalDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, 1 Deaconess Road, 2nd Floor, Boston, MA, 02215, USA.
Katherine L BoyleDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, 1 Deaconess Road, 2nd Floor, Boston, MA, 02215, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrescription drug monitoring programs (PDMPs) exist in 49 states to guide opioid prescribing. In 40 states, clinicians must check the PDMP prior to prescribing an opioid. Data on mandated PDMP checks show mixed results on opioid prescribing.

objectivesThis study sought to examine the impact of the Massachusetts mandatory PDMP check on opioid prescribing for discharges from an urban tertiary emergency department (ED).

methodsThis was a retrospective cohort study of discharges from one ED from 7/1/2010-10/15/2018. The primary outcome was the monthly percentage of patients discharged from the ED with an opioid prescription. The intervention was Massachusetts mandating a PDMP check for all opioid prescriptions. Prescribing was compared pre- and post-mandate. Interrupted time series (ITS) analysis accounted for known declining trends in opioid prescribing.

resultsOf 273,512 ED discharges, 35,050 (12.8%) received opioid prescriptions. Mean monthly opioid prescribing decreased post-intervention from 15.1% (SD ± 3.5%) to 5.1% (SD ± 0.9%; p < 0.001). ITS showed equal pre and post-intervention slopes (-0.002, p = 0.819). A small immediate decrease occurred in prescribing around the mandated check: a 3-month level effect decrease of 0.018 (p = 0.039), 6-month level effect 0.019 (p = 0.023), and a 12-month level effect of 0.020 (p = 0.019). The 24-month level effect was not decreased.

conclusionPrior to the mandated PDMP check, ED opioid prescribing was declining. The mandate did not change the rate of decline but was associated with a non-sustained drop in opioid prescribing immediately following enactment.

Indexed as

AdolescentAdultAgedAged, 80 and overAnalgesics, OpioidCohort StudiesDrug PrescriptionsEmergency Service, HospitalFemaleForecastingHospitals, UrbanHumansMaleMassachusettsMiddle AgedPrescription Drug Monitoring ProgramsAnalgesics, OpioidEmergency departmentOpioidPrescription drug monitoring program

Identifiers

PMID33821434
PMCPMC8206309

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.