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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021

Comparing the measurement properties of the EQ-5D-5L and the EQ-5D-3L in hypertensive patients living in rural China.

Jie Jiang, Yanming Hong, Tiantian Zhang, Zhihao Yang, Tengfei Lin, Zhuoru Liang, Peiyao Lu, Lishun Liu, Binyan Wang, Yongmei Xu and 1 more

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Is EQ-5D-5L better than EQ-5D-3L? A comparison of descriptive systems and utility scores in patients with kidney chronic disease.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
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  8. Health-related quality of life assessed by EQ-5D-5L and its determinants among rural adults: result from the Henan rural cohort study.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
    Article
  9. A head-to-head comparison of the measurement properties of EQ-5D-3L and EQ-5D-5L in Chinese family caregivers of cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
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  12. Comparing EQ-5D-3L and EQ-5D-5L in measuring the HRQoL burden of 4 health conditions in China.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Article
  13. Article
  14. Validating the Well-Being of Older People (WOOP) Instrument in China.International journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jie Jiang *College of Pharmacy, Jinan University, Guangzhou, People's Republic of China.
Yanming Hong *College of Pharmacy, Jinan University, Guangzhou, People's Republic of China.
Tiantian Zhang *College of Pharmacy, Jinan University, Guangzhou, People's Republic of China.
Zhihao YangCollege of Pharmacy, Jinan University, Guangzhou, People's Republic of China.
Tengfei LinBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, People's Republic of China.
Zhuoru LiangCollege of Pharmacy, Jinan University, Guangzhou, People's Republic of China.
Peiyao LuCollege of Pharmacy, Jinan University, Guangzhou, People's Republic of China.
Lishun LiuBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, People's Republic of China.
Binyan WangShenzhen Evergreen Medical Institute, Shenzhen, People's Republic of China.
Yongmei XuSchool of Management, Jinan University, Guangzhou, People's Republic of China. 80613111@qq.com.
Nan LuoSaw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore. ephln@nus.edu.sg.ORCID http://orcid.org/0000-0002-4610-1195

Funding

Natural Science Foundation of Guangdong Province 2020A1515010990Science and Technology Program of Guangzhou, China 201704020198
6 · The paper itself

Abstract

purposeThe purpose of this study was to compare the measurement properties of two versions of EQ-5D (i.e.EQ-5D-3L and EQ-5D-5L) in hypertensive patients in rural China.

methodsA cross-sectional survey was carried out in hypertensive patients in rural China. We compared the ceiling effects, redistribution properties, informativity, known-groups validity, and relative efficiency of the 3L and 5L and examined their agreement.

resultsA total of 11,412 patients were enrolled in our study. The mean EQ-5D index score was 0.84 (SD 0.21) according to the 5L and 0.86 (SD 0.17) according to the 3L. A good agreement was observed between the 3L and 5L. The overall ceiling effect decreased from 46.4% (3L) to 29.4% (5L). The Shannon index, H' improved in all dimensions when used 5L. When used 3L, the median responses of all groups were consistent with 5L across the three dimensions of 'mobility', 'self-care', 'usual activities', while the median responses were inconsistent for the 'pain/discomfort' and 'anxiety/depression' dimensions. The 3L performed better in eight comorbidities in terms of F-statistics and six comorbidities in terms of the area under the receiver operating characteristic curves (AUROCs). The 5L performed better both in terms of the F-statistics and AUROCs in age, education level, anti-hypertensive medication use.

conclusionTaking all comparisons into account, we recommend the EQ-5D-5L for use in patients with hypertension in rural China.

Indexed as

AdolescentAdultAgedAged, 80 and overChinaCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedPsychometricsQuality of LifeReproducibility of ResultsRural PopulationSurveys and QuestionnairesChinaEQ-5D-3LEQ-5D-5LHealth-related quality of lifeHypertension

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.