Evidence map›Paper›PMID 33821386›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2022

Clinical characteristics and long-term outcomes of catheter ablation in young adults with atrial fibrillation.

Michael Ghannam, Aman Chugh, David J Bradley, Thomas Crawford, Rakesh Latchamsetty, Hamid Ghanbari, Ryan Cunnane, Mohammed Saeed, Krit Jongnarangsin, Frank Pelosi and 2 more

Erratum issuedOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Michael GhannamCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA.
Aman ChughCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA.
David J BradleyCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA.
Thomas CrawfordCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA.
Rakesh LatchamsettyCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA.
Hamid GhanbariCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA.
Ryan CunnaneCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA.
Mohammed SaeedCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA.
Krit JongnarangsinCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA.
Frank PelosiCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA.
Fred MoradyCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA.
Hakan OralCardiac Arrhythmia Service, Cardiovascular Medicine, Cardiovascular Center, University of Michigan, SPC 5853, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5853, USA. oralh@med.umich.edu.
University of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aim to describe the long-term safety and efficacy of catheter ablation (CA) in young patients (<30 years) with atrial fibrillation (AF).

methodsThis was a retrospective study of patients aged 18-30 who underwent CA for AF, and clinical characteristics and long-term outcomes are reported. Survival analyses were performed between the study group and a propensity-matched older cohort (>30 years, mean age: 58±10 years).

resultsFrom January 2000 to January 2019, a 1st CA (radiofrequency energy n=72, cryoballoon n=10), was performed in 82 patients (mean age 26±4 years, paroxysmal n=61, persistent n=14, longstanding persistent n=7), among 6336 consecutive patients with AF. During a follow-up of 5±5 years, 56% and 30% of the patients with paroxysmal and non-paroxysmal AF were arrhythmia free without antiarrhythmic drug (AAD) therapy after a single CA (P=0.02). After 1.5±0.8 CA procedures, 76% and 75% of the patients with paroxysmal AF and non-paroxysmal AF were arrhythmia free without AADs (P=0.54). Compared to a propensity-matched group of older patients, young patients were as likely to remain in sinus rhythm after CA (P=0.47), however after fewer repeat CAs (1.5±0.8 vs 1.9±0.9, P<0.009). There were no long-term adverse outcomes associated with CA.

conclusionsCA is a safe and effective treatment of AF in young patients with comparable outcomes to the older patients, however after fewer procedures.

Indexed as

Atrial FibrillationCatheter AblationAdultAgedAnti-Arrhythmia AgentsHumansMiddle AgedRecurrenceRetrospective StudiesTreatment OutcomeYoung AdultAnti-Arrhythmia AgentsAtrial fibrillationCatheter ablationCryoballoon catheter ablationPersistent atrial fibrillationRadiofrequency catheter ablationYoung adults

Identifiers

PMID33821386
OpenAlexW3144422685

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.