Evidence map›Paper›PMID 33821269›Full record

ArticlebioRxiv : the preprint server for biology2021

Sex differences in lung imaging and SARS-CoV-2 antibody responses in a COVID-19 golden Syrian hamster model.

Santosh Dhakal, Camilo A Ruiz-Bedoya, Ruifeng Zhou, Patrick Creisher, Jason Villano, Kirsten Littlefield, Jennie Castillo, Paula Marinho, Anne Jedlicka, Alvaro Ordonez and 18 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 12 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors at 1 institution in 1 country.

Camilo A Ruiz-Bedoya
Ruifeng Zhou
Patrick Creisher
Jason Villano
Kirsten Littlefield
Jennie Castillo
Paula Marinho
Anne Jedlicka
Alvaro Ordonez
Natalia Majewska
Michael Betenbaugh
Kelly Flavahan
Alice Mueller
Monika Looney
Darla Quijada
Filipa Mota
Sarah E Beck
Jacqueline K Brockhurst
Alicia Braxton
Natalie Castell
Franco D'Alessio
Kelly A Metcalf PateORCID 0000-0003-4799-4631
Petros C Karakousis
Joseph L Mankowski
Sabra L Klein
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), more severe outcomes are reported in males compared with females, including hospitalizations and deaths. Animal models can provide an opportunity to mechanistically interrogate causes of sex differences in the pathogenesis of SARS-CoV-2. Adult male and female golden Syrian hamsters (8-10 weeks of age) were inoculated intranasally with 10

Identifiers

PMID33821269
PMCPMC8020969
OpenAlexW3145100466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.