Evidence map›Paper›PMID 33820956›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2021

Dopamine D

Hewang Lee, Xiaoliang Jiang, Imran Perwaiz, Peiying Yu, Jin Wang, Ying Wang, Maik Hüttemann, Robin A Felder, David R Sibley, Brian M Polster and 5 more

Open access · greenAbstract read
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Reactive oxygen species in hypertension.Nature reviews. Cardiology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Dopamine, Immunity, and Disease.Pharmacological reviews · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 2 countries.

Hewang LeeDepartment of Medicine, School of Medicine & Health Sciences, George Washington University, Washington, DC, USA.
Xiaoliang JiangInstitute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Comparative Medicine Center, Peking Union Medical College, Beijing, China.
Imran PerwaizInstitute of Heart and Vessel Diseases, Affiliated Second Hospital, Dalian Medical University, Dalian, China.
Peiying YuDivision of Nephrology, Department of Medicine, School of Medicine, University of Maryland, Baltimore, MD, USA.
Jin WangInstitute of Heart and Vessel Diseases, Affiliated Second Hospital, Dalian Medical University, Dalian, China.
Ying WangInstitute of Heart and Vessel Diseases, Affiliated Second Hospital, Dalian Medical University, Dalian, China.
Maik HüttemannCenter for Molecular Medicine and Genetics and Cardiovascular Research Institute, School of Medicine, Wayne State University, Detroit, MI, USA.
Robin A FelderDepartment of Pathology, University of Virginia Health Sciences Center, Charlottesville, VA, USA.
David R SibleyMolecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Brian M PolsterDepartment of Anesthesiology, School of Medicine, University of Maryland, Baltimore, MD, USA.
Selim RozyyevDepartment of Medicine, School of Medicine & Health Sciences, George Washington University, Washington, DC, USA.
Ines ArmandoDepartment of Medicine, School of Medicine & Health Sciences, George Washington University, Washington, DC, USA.
Zhiwei YangInstitute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Comparative Medicine Center, Peking Union Medical College, Beijing, China.
Peng QuInstitute of Heart and Vessel Diseases, Affiliated Second Hospital, Dalian Medical University, Dalian, China.
Pedro A JoseDepartment of Medicine, School of Medicine & Health Sciences, George Washington University, Washington, DC, USA. pjose@mfa.gwu.edu.
Dalian Medical University · CNUniversity of Maryland, Baltimore · USGeorge Washington University · USChinese Academy of Medical Sciences & Peking Union Medical College · CNGeorgetown University Medical Center · USInstitute of Laboratory Animal Science · CNNational Institute of Neurological Disorders and Stroke · USSecond Affiliated Hospital of Dalian Medical University · CNUniversity of Virginia · USWayne State University · US

Funding

Molecular And Pharmacological Studies Of Dopamine ReceptorsZIANS002263 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI SIBLEY, DAVID · 2009 to 2025
$37.4M
Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GILDEA, JOHN JOSEPH · 2004 to 2020
$31.8M
RENAL DOPAMINE-1 RECEPTOR DEFECT IN HYPERTENSIONR01DK039308 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 1987 to 2020
$7.4M
Renal Dopamine Receptor & RegulationR37HL023081 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 2007 to 2016
$4.3M
GRK4 & Development of Salt SensitivityR01HL092196 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI ARMANDO, INES, JOSE, PEDRO A. · 2008 to 2017
$3.6M
Molecular &Pharmacological Studies Of Dopamine ReceptorZ01NS002263 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI SIBLEY, DAVID R. · 1985 to 2008
$3.1M
Lipid rafts, dopamine 1 receptor, and hypertensionR01DK119652 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI JOSE, PEDRO A. · 2020 to 2023
$2.6M
RENAL DOPAMINE RECEPTOR REGULATION AND FUNCTIONR01HL023081 · NHLBI · GEORGETOWN UNIVERSITY · PI JOSE, PEDRO A. · 1985 to 2006
$2.4M
Role of Dopamine D2 Receptor in Renal Inflammation and InjuryR01DK090918 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI ARMANDO, INES · 2011 to 2015
$1.7M
Intramural NIH HHS Z01 NS002263NHLBI NIH HHS P01 HL074940NHLBI NIH HHS R01 HL023081NHLBI NIH HHS R01 HL092196NHLBI NIH HHS R37 HL023081NIDDK NIH HHS R01 DK039308NIDDK NIH HHS R01 DK090918NIDDK NIH HHS R01 DK119652
6 · The paper itself

Abstract

Overproduction of reactive oxygen species (ROS) plays an important role in the pathogenesis of hypertension. The dopamine D

Indexed as

MitochondriaReactive Oxygen SpeciesReceptors, Dopamine D5AnimalsAutophagyCyclic AMPFenoldopamHEK293 CellsHumansKidneyMiceCyclic AMPDrd5 protein, mouseFenoldopamReactive Oxygen SpeciesReceptors, Dopamine D5AutophagyDopamine D5 receptorHypertensionMitochondriaReactive oxygen species

Identifiers

PMID33820956
PMCPMC8369611
OpenAlexW3147166794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.