Evidence map›Paper›PMID 33820883›Full record

ArticleMolecules and cells2021

Jangham Jung, Eunhee Kim, Myungchull Rhee

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jangham JungDepartment of Life Science, BK21 Plus Program, Graduate School, Chungnam National University, Daejeon 34134, Korea.ORCID https://orcid.org/0000-0003-2806-3698
Eunhee KimDepartment of Biological Sciences, College of Bioscience and Biotechnology, Chungnam National University, Daejeon 34134, Korea.ORCID https://orcid.org/0000-0002-7738-1222
Myungchull RheeDepartment of Life Science, BK21 Plus Program, Graduate School, Chungnam National University, Daejeon 34134, Korea.ORCID https://orcid.org/0000-0002-4595-7573
Chungnam National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To define novel networks of Parkinson's disease (PD) pathogenesis, the substantia nigra pars compacta of A53T mice, where a death-promoting protein, FAS-associated factor 1 was ectopically expressed for 2 weeks in the 2-, 4-, 6-, and 8-month-old mice, and was subjected to transcriptomic analysis. Compendia of expression profiles and a hierarchical clustering heat map of differentially expressed genes associated with PD were bioinformatically generated. Transcripts level of a particular gene was fluctuated by 20, 60, and 0.75 fold in the 4-, 6-, and 8-month-old mice compared to the 2 months old. Because the gene contained Kelch domain, it was named as

Indexed as

AnimalsDopaminergic NeuronsGene Regulatory NetworksMiceNeurogenesisParkinson DiseaseZebrafishFAF1Kapd (Kelch-containing protein associated with PD)midbrain dopaminergic neuronsnext-generation sequencingParkinson’s disease

Identifiers

PMID33820883
PMCPMC8112167
OpenAlexW3140685673

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.