ArticleProceedings of the National Academy of Sciences of the United States of America2021
Impacts of biodiversity and biodiversity loss on zoonotic diseases.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 132 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
132 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Hepatozoon (Eucoccidiorida: Hepatozoidae) in wild mammals of the Americas: a systematic review.Parasites & vectors · 2024Pooled it
- Zoonotic pathogens in wild Asian primates: a systematic review highlighting research gaps.Frontiers in veterinary science · 2024Pooled it
- Toward One Health: a spatial indicator system to model the facilitation of the spread of zoonotic diseases.Frontiers in public health · 2023Pooled it
- Article
- Virome Diversity in Three Bat Species in Different Environments in Southern Spain.Microorganisms · 2026Article
- Drivers of Viral Spillover: An Examination of How Pathogens Spread.Pathogens (Basel, Switzerland) · 2026Review
- Landscape Fragmentation Shapes Zoonotic Malaria Spillover Risk During Deforestation.EcoHealth · 2026Article
- Species Extinction, Biodiversity, Human Health, and Inevitable Role of Lifestyle Medicine: A Narrative Review.American journal of lifestyle medicine · 2026Review
- Article
- Applying one health approaches to addressing disease risks in wildlife trade: Insights from a special issue.One health (Amsterdam, Netherlands) · 2026Article
- From animal ethics to climate change: Integrating human-animal-studies and one health into medical education.One health (Amsterdam, Netherlands) · 2026Article
- Rethinking One Health: Microbial Foundations for Ecological Governance.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026Review
- Paleopathology Meets Public Health: Deep-Time Syndemics and the Ecology of Emerging Infections.Pathogens (Basel, Switzerland) · 2026Review
- Medium- and Large-sized Mammals on the Plateau: An Evolutionary Crucible for Zoonotic Pathogens - Ecological Drivers, Adaptive Evolution, and One Health Control.Microbial ecology · 2026Review
- Zoonoethics and Inclusive One Health Governance for H5N1 Panzootic: From Animal Culling to Co-responsibility.Public health ethics · 2026Article
- Ticks and tick-borne diseases: A call for comprehensive tick surveillance in India under One Health approach.The Indian journal of medical research · 2026Review
- Environmental degradation as a recipe for emerging viral diseases: implications for global health.One health outlook · 2026Review
- Detection of Wencheng shrew virus and cardiovirus from small mammals in Myanmar.Scientific reports · 2026Article
- Land use gradients drive spatial variation in Lassa fever host communities in the Eastern Province of Sierra Leone.The Journal of animal ecology · 2026Article
- Advances in rapid detection technologies for zoonotic diseases: a one health-oriented review.Frontiers in cellular and infection microbiology · 2026Review
72 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zoonotic diseases are infectious diseases of humans caused by pathogens that are shared between humans and other vertebrate animals. Previously, pristine natural areas with high biodiversity were seen as likely sources of new zoonotic pathogens, suggesting that biodiversity could have negative impacts on human health. At the same time, biodiversity has been recognized as potentially benefiting human health by reducing the transmission of some pathogens that have already established themselves in human populations. These apparently opposing effects of biodiversity in human health may now be reconcilable. Recent research demonstrates that some taxa are much more likely to be zoonotic hosts than others are, and that these animals often proliferate in human-dominated landscapes, increasing the likelihood of spillover. In less-disturbed areas, however, these zoonotic reservoir hosts are less abundant and nonreservoirs predominate. Thus, biodiversity loss appears to increase the risk of human exposure to both new and established zoonotic pathogens. This new synthesis of the effects of biodiversity on zoonotic diseases presents an opportunity to articulate the next generation of research questions that can inform management and policy. Future studies should focus on collecting and analyzing data on the diversity, abundance, and capacity to transmit of the taxa that actually share zoonotic pathogens with us. To predict and prevent future epidemics, researchers should also focus on how these metrics change in response to human impacts on the environment, and how human behaviors can mitigate these effects. Restoration of biodiversity is an important frontier in the management of zoonotic disease risk.
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