Evidence map›Paper›PMID 33820813›Full record

ArticleInfection and immunity2021

Intracellular Passage Triggers a Molecular Response in Brucella abortus That Increases Its Infectiousness.

Pamela Altamirano-Silva, Marlen Cordero-Serrano, Joselyn Méndez-Montoya, Carlos Chacón-Díaz, Caterina Guzmán-Verri, Edgardo Moreno, Esteban Chaves-Olarte

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. AMicroorganisms · 2023
    Article
  6. Article
  7. Article
  8. TheFrontiers in microbiology · 2023
    Article
  9. Phenotypes controlled by theFrontiers in microbiology · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Pamela Altamirano-SilvaCentro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.
Marlen Cordero-SerranoCentro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.
Joselyn Méndez-MontoyaCentro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.
Carlos Chacón-DíazCentro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.
Caterina Guzmán-VerriPrograma de Investigación en Enfermedades Tropicales, Escuela de Medicina Veterinaria, Universidad Nacional, Heredia, Costa Rica.
Edgardo MorenoPrograma de Investigación en Enfermedades Tropicales, Escuela de Medicina Veterinaria, Universidad Nacional, Heredia, Costa Rica.
Esteban Chaves-OlarteCentro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.
Universidad de Costa Rica · CRUniversidad Nacional · CR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brucella abortus is a facultatively extracellular-intracellular pathogen that encounters a diversity of environments within the host cell. We report that bacteria extracted from infected cells at late stages (48 h postinfection) of the intracellular life cycle significantly increase their ability to multiply in new target cells. This increase depends on early interaction with the cell surface, since the bacteria become more adherent and penetrate more efficiently than

Indexed as

Host-Pathogen InteractionsAnimalsAutophagosomesBacterial AdhesionBacterial ProteinsBrucella abortusBrucellosis, BovineCattleGene Expression Regulation, BacterialMacrophagesType IV Secretion SystemsVirulenceBacterial ProteinsType IV Secretion Systemsadherentbrucellosishost cellshost-pathogen interactionsinfectiousnessintracellular life cycletranscriptional regulator VjbRtwo-component systemtype IV secretion systemvirulence circuit

Identifiers

PMID33820813
PMCPMC8373234
OpenAlexW3151233400

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.