Evidence map›Paper›PMID 33820777›Full record

ReviewCancer discovery2021

Mechanisms of Resistance to KRAS

Neal S Akhave, Amadeo B Biter, David S Hong

Abstract readReview
In one paragraph

Review in Cancer discovery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Small-molecule degraders for oncogenic KRASNature communications · 2026
    Article
  10. Systematic and precise interventions for KRAS-mutant cancers.Experimental hematology & oncology · 2026
    Review
  11. Therapeutic advances with KRASCancer gene therapy · 2026
    Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. USP10-mediated deubiquitination and activation ofActa pharmaceutica Sinica. B · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Distinct molecular subtypes of KRASClinical and translational medicine · 2025
    Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Neal S AkhaveDivision of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Amadeo B BiterDepartment of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
David S HongDepartment of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas. dshong@mdanderson.org.ORCID 0000-0001-8721-1609

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug Resistance, NeoplasmAntineoplastic AgentsCarcinoma, Non-Small-Cell LungHumansLung NeoplasmsProtein Kinase InhibitorsProto-Oncogene Proteins p21(ras)Antineoplastic AgentsProtein Kinase InhibitorsProto-Oncogene Proteins p21(ras)

Identifiers

PMID33820777
PMCPMC8178176

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.