Evidence map›Paper›PMID 33820773›Full record

ArticleAntimicrobial agents and chemotherapy2021

Abigail M Rubio, Ellen G Kline, Chelsea E Jones, Liang Chen, Barry N Kreiswirth, M Hong Nguyen, Cornelius J Clancy, Vaughn S Cooper, Ghady Haidar, Daria Van Tyne and 1 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 61 citations in OpenAlex.

  1. L2 β-lactamase contributes to ceftolozane-tazobactam resistance inAntimicrobial agents and chemotherapy · 2026
    Article
  2. Variable phage susceptibility ofbioRxiv : the preprint server for biology · 2026
    Article
  3. Beyond Resistance Genes:Life (Basel, Switzerland) · 2026
    Review
  4. Ceftazidime-avibactam resistance evolution inAntimicrobial agents and chemotherapy · 2026
    Article
  5. Article
  6. A novel mechanism of ceftolozane-tazobactam resistance inbioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Review
  9. Effectiveness of imipenem-relebactam for multidrug-resistantAntimicrobial agents and chemotherapy · 2025
    Observational
  10. Article
  11. Clinical Analysis ofJournal of clinical medicine · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Modern antiseptics against multidrug-resistantFrontiers in microbiology · 2025
    Article
  16. Article
  17. Antimicrobial agents and chemotherapy · 2024
    Article
  18. Article
  19. Clinical outcomes and emergence of resistance ofAntimicrobial agents and chemotherapy · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Abigail M RubioDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Ellen G KlineDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Chelsea E JonesDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Liang ChenHackensack-Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, USA.
Barry N KreiswirthHackensack-Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, USA.
M Hong NguyenDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Cornelius J ClancyDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Vaughn S CooperDepartment of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-7726-0765
Ghady HaidarDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-0634-8211
Daria Van TyneDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-7284-0103
Ryan K ShieldsDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA shieldsrk@upmc.edu.ORCID 0000-0001-9794-5665
University of Pittsburgh · USHackensack Meridian Health · US

Funding

Institutional Career Development CoreKL2TR001856 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RAY, KRISTIN N, RUBIO, DORIS M · 2016 to 2025
$13.8M
Predicting the emergence of antibiotic resistance through multi-omics approaches and Immune System-surveillanU01AI124302 · NIAID · BOSTON COLLEGE · PI BENTO, JOSE, COOPER, VAUGHN · 2016 to 2020
$10.2M
The molecular basis of the epidemic blaKPC gene KlebsiellaR01AI090155 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI KREISWIRTH, BARRY NEAL · 2011 to 2021
$7.2M
The Gut Microbiome in Carbapenem-Resistant Enterobacteriaceae Colonization, Persistence, Infection, and Tolerance after Lung or Liver TransplantationK23AI154546 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HAIDAR, GHADY · 2021 to 2025
$896k
Caspofungin pharmacokinetics-pharmacodynamics during intra-adbominal candidiasisK08AI114883 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHIELDS, RYAN K · 2015 to 2019
$858k
Use of site-specific pharmacokinetics to optimize antibiotic combinations and prevent the emergence of resistance against CRER21AI151363 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHIELDS, RYAN K · 2021 to 2022
$431k
Characterization and suppression of resistance to new CRE agentsR03AI144636 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHIELDS, RYAN K · 2019 to 2020
$157k
NCATS NIH HHS KL2 TR001856NIAID NIH HHS K08 AI114883NIAID NIH HHS K23 AI154546NIAID NIH HHS R01 AI090155NIAID NIH HHS R03 AI144636NIAID NIH HHS R21 AI151363NIAID NIH HHS U01 AI124302
6 · The paper itself

Abstract

We compared the

Indexed as

Pseudomonas aeruginosaPseudomonas InfectionsAnti-Bacterial AgentsCephalosporinsDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsTazobactamAnti-Bacterial AgentsceftolozaneCephalosporinsTazobactamantibiotic resistanceceftolozane-tazobactamimipenem-relebactamPseudomonas aeruginosa

Identifiers

PMID33820773
PMCPMC8315963
OpenAlexW3112147994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.