Evidence map›Paper›PMID 33820568›Full record

ReviewAIDS research and therapy2021

The role of CD38 in HIV infection.

Liqi Lu, Jie Wang, Qian Yang, Xiuqiao Xie, Yuanshuai Huang

Open access · goldAbstract readReview
In one paragraph

Review in AIDS research and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  3. NADThe Journal of general virology · 2026
    Review
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  19. Regulation of CD38 on Multiple Myeloma and NK Cells by Monoclonal Antibodies.International journal of biological sciences · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Liqi LuDepartment of Transfusion, The Affiliated Hospital of Southwest Medical University, 25 Taiping Road, Luzhou, Sichuan, 646000, People's Republic of China.
Jie WangDepartment of Transfusion, The Affiliated Hospital of Southwest Medical University, 25 Taiping Road, Luzhou, Sichuan, 646000, People's Republic of China.
Qian YangDepartment of Clinical Laboratory, The First People's Hospital of Longquanyi District, Chengdu, 201 Third Yihe Group, Longquanyi District, Chengdu, Sichuan, 610100, People's Republic of China.
Xiuqiao XieDepartment of Transfusion, The Affiliated Hospital of Southwest Medical University, 25 Taiping Road, Luzhou, Sichuan, 646000, People's Republic of China.
Yuanshuai HuangDepartment of Transfusion, The Affiliated Hospital of Southwest Medical University, 25 Taiping Road, Luzhou, Sichuan, 646000, People's Republic of China. hys@live.cn.
Affiliated Hospital of Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widely-expressed molecule CD38 is a single-stranded type II transmembrane glycoprotein that is mainly involved in regulating the differentiation and activation state of the cell. CD38 has broad and complex functions, including enzymatic activity, intercellular signal transduction, cell activation, cytokine production, receptor function and adhesion activity, and it plays an important role in the physiological and pathological processes of many diseases. Many studies have shown that CD38 is related to the occurrence and development of HIV infection, and CD38 may regulate its progression through different mechanisms. Therefore, investigating the role of CD38 in HIV infection and the potential signaling pathways that are involved may provide a new perspective on potential treatments for HIV infection. In the present review, the current understanding of the roles CD38 plays in HIV infection are summarized. In addition, the specific role of CD38 in the process of HIV infection of human CD4

Indexed as

ADP-ribosyl Cyclase 1HIV InfectionsCD4-Positive T-LymphocytesHumansADP-ribosyl Cyclase 1Abnormal immune activationARTCD38 moleculeHIV

Identifiers

PMID33820568
PMCPMC8021004
OpenAlexW3145897969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.