ArticleEnvironmental health : a global access science source2021
Extreme temperature and out-of-hospital-cardiac-arrest. Nationwide study in a hot climate country.
Article in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 5 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Association between ambient temperature and out-of-hospital cardiac arrest: a systematic review and meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Thermal indices for assessing the impact of outdoor thermal environments on human health: a systematic review of epidemiological studies.International journal of biometeorology · 2025Pooled it
- Air Pollution and Temperature: a Systematic Review of Ubiquitous Environmental Exposures and Sudden Cardiac Death.Current environmental health reports · 2023Pooled it
- Heat, heatwaves, and ambulance service use: a systematic review and meta-analysis of epidemiological evidence.International journal of biometeorology · 2023Pooled it
- Heatwave Definition and Impact on Cardiovascular Health: A Systematic Review.Public health reviews · 2023Pooled it
- Ambient air temperature and out-of-hospital cardiac arrest: A national case-crossover study.Journal of internal medicine · 2026Article
- Interaction of Extreme Temperature Events and Nitrogen Dioxide on Out-of-Hospital Cardiac Arrest in a Subtropical Megacity: A Time-Series Analysis.Journal of the American Heart Association · 2026Article
- Influence of extreme temperatures on out-of-hospital cardiac arrest cases in Hungary: a national time-series analysis.Resuscitation plus · 2026Article
- The effect of climate extremes on disability, depression, and cognitive decline in middle-aged and older Chinese adults under different healthy lifestyle.Journal of global health · 2025Observational
- Lethal Heat and Humidity Events.Annual review of environment and resources · 2025Article
- Short-term exposures to temperature and risk of sudden cardiac death in women: A case-crossover analysis in the Nurses' Health Study.Environmental epidemiology (Philadelphia, Pa.) · 2024Article
- The Impact of Climate Change and Extreme Weather Conditions on Cardiovascular Health and Acute Cardiovascular Diseases.Journal of clinical medicine · 2024Review
- Extreme Temperature Exposure and Risks of Preterm Birth Subtypes Based on a Nationwide Survey in China.Environmental health perspectives · 2023Article
- The impact of non-optimum temperatures, heatwaves and cold spells on out-of-hospital cardiac arrest onset in a changing climate in China: a multi-center, time-stratified, case-crossover study.The Lancet regional health. Western Pacific · 2023Article
- Association between extreme temperatures and out-of-hospital cardiac arrest: A time-stratified case-crossover study in Korea.The journal of climate change and healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOut-of-hospital-cardiac arrest (OHCA) is frequently linked to environmental exposures. Climate change and global warming phenomenon have been found related to cardiovascular morbidity, however there is no agreement on their impact on OHCA occurrence. In this nationwide analysis, we aimed to assess the incidence of the OHCA events attended by emergency medical services (EMS), in relation to meteorological conditions: temperature, humidity, heat index and solar radiation.
methodsWe analyzed all adult cases of OHCA in Israel attended by EMS during 2016-2017. In the case-crossover design, we compared ambient exposure within 72 h prior to the OHCA event with exposure prior to the four control times using conditional logistic regression in a lag-distributed non-linear model.
resultsThere were 12,401 OHCA cases (68.3% were pronounced dead-on-scene). The patients were on average 75.5 ± 16.2 years old and 55.8% of them were males. Exposure to 90th and 10th percentile of temperature adjusted to humidity were positively associated with the OHCA with borderline significance (Odds Ratio (OR) =1.20, 95%CI 0.97; 1.49 and OR 1.16, 95%CI 0.95; 1.41, respectively). Relative humidity below the 10th percentile was a risk factor for OHCA, independent of temperature, with borderline significance (OR = 1.16, 95%CI 0.96; 1.38). Analysis stratified by seasons revealed an adverse effect of exposure to 90th percentile of temperature when estimated in summer (OR = 3.34, 95%CI 1.90; 3.5.86) and exposure to temperatures below 10th percentile in winter (OR = 1.75, 95%CI 1.23; 2.49). Low temperatures during a warm season and high temperatures during a cold season had a protective effect on OHCA. The heat index followed a similar pattern, where an adverse effect was demonstrated for extreme levels of exposure.
conclusionsEvolving climate conditions characterized by excessive heat and low humidity represent risk factors for OHCA. As these conditions are easily avoided, by air conditioning and behavioral restrictions, necessary prevention measures are warranted.
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