Evidence map›Paper›PMID 33819964›Full record

ArticleZhongguo fei ai za zhi = Chinese journal of lung cancer2021

[Clinical Recommendations for Perioperative Immunotherapy-induced Adverse Events in Patients with Non-small Cell Lung Cancer].

Jun Ni, Miao Huang, Li Zhang, Nan Wu, Chunxue Bai, Liang'an Chen, Jun Liang, Qian Liu, Jie Wang, Yilong Wu and 41 more

Open access · greenAbstract readConsensus Statement
In one paragraph

Article in Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 citations in OpenAlex.

  1. Observational
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

51 authors at 14 institutions in 1 country.

Jun Ni *Peking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Miao Huang *Department of Thoracic Surgery, Peking University Cancer Hospital, Beijing 100142, China.
Li ZhangPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Nan WuDepartment of Thoracic Surgery, Peking University Cancer Hospital, Beijing 100142, China.
Chunxue BaiDepartment of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Liang'an ChenThe First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Jun LiangPeking University International Hospital, Beijing 102206, China.
Qian LiuTianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.
Jie WangState Key Laboratory of Molecular Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Yilong WuDepartment of Pulmonary Cancer, Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510000, China.
Fengchun ZhangPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Shuyang ZhangPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Chun ChenDepartment of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou 350001, China.
Jun ChenDepartment of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin 300052, China.
Wentao FangDepartment of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China.
Shugeng GaoState Key Laboratory of Molecular Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Jian HuDepartment of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Tao JiangDepartment of Thoracic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China.
Shanqing LiPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Hecheng LiDepartment of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Yongde LiaoDepartment of Thoracic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei 430022, China.
Yang LiuThe First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Deruo LiuChina-Japan Friendship Hospital, Beijing 100029, China.
Hongxu LiuDepartment of Thoracic Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang 110001, China.
Jianyang LiuDepartment of Thoracic Surgery-1, Jilin Cancer Hospital, Changchun 130012, China.
Lunxu LiuDepartment of Cardiovascular and Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Mengzhao WangPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Changli WangDepartment of Lung Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Fan YangPeking University People's Hospital, Beijing 100044, China.
Yue YangDepartment of Thoracic Surgery, Peking University Cancer Hospital, Beijing 100142, China.
Lanjun ZhangDepartment of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China.
Xiuyi ZhiDepartment of Thoracic Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Wenzhao ZhongDepartment of Pulmonary Cancer, Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510000, China.
Yuzhou GuanPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Xiaoxiao GuoPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Chunxia HePeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Shaolei LiDepartment of Thoracic Surgery, Peking University Cancer Hospital, Beijing 100142, China.
Yue LiPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Naixin LiangPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Fangliang LuDepartment of Thoracic Surgery, Peking University Cancer Hospital, Beijing 100142, China.
Chao LvDepartment of Thoracic Surgery, Peking University Cancer Hospital, Beijing 100142, China.
Wei LvPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Xiaoyan SiPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Fengwei TanState Key Laboratory of Molecular Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Hanping WangPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Jiangshan WangPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Shi YanDepartment of Thoracic Surgery, Peking University Cancer Hospital, Beijing 100142, China.
Huaxia YangPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Huijuan ZhuPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Junling ZhuangPeking Union Medical Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Minglei ZhuoDepartment of Thoracic Surgery, Peking University Cancer Hospital, Beijing 100142, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNChinese PLA General Hospital · CNPeking University · CNAir Force Medical University · CNCapital Medical University · CNChina-Japan Friendship Hospital · CNFirst Affiliated Hospital Zhejiang University · CNFujian Medical University · CNRuijin Hospital · CNShanghai Chest Hospital · CNSun Yat-sen University Cancer Center · CNThe First Affiliated Hospital, Sun Yat-sen University · CNTianjin Medical University General Hospital · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerioperative treatment has become an increasingly important aspect of the management of patients with non-small cell lung cancer (NSCLC). Small-scale clinical studies performed in recent years have shown improvements in the major pathological remission rate after neoadjuvant therapy, suggesting that it will soon become an important part of NSCLC treatment. Nevertheless, neoadjuvant immunotherapy may be accompanied by serious adverse reactions that lead to delay or cancelation of surgery, additional illness, and even death, and have therefore attracted much attention. The purpose of the clinical recommendations is to form a diagnosis and treatment plan suitable for the current domestic medical situation for the immune-related adverse event (irAE).

methodsThis recommendation is composed of experts in thoracic surgery, oncologists, thoracic medicine and irAE related departments (gastroenterology, respirology, cardiology, infectious medicine, hematology, endocrinology, rheumatology, neurology, dermatology, emergency section) to jointly complete the formulation. Experts make full reference to the irAE guidelines, large-scale clinical research data published by thoracic surgery, and the clinical experience of domestic doctors and publicly published cases, and repeated discussions in multiple disciplines to form this recommendation for perioperative irAE.

resultsThis clinical recommendation covers the whole process of prevention, evaluation, examination, treatment and monitoring related to irAE, so as to guide the clinical work comprehensively and effectively.

conclusionsPerioperative irAE management is an important part of immune perioperative treatment of lung cancer. With the continuous development of immune perioperative treatment, more research is needed in the future to optimize the diagnosis and treatment of perioperative irAE.

Indexed as

Carcinoma, Non-Small-Cell LungChinaClinical Trials as TopicHumansImmunotherapyLung NeoplasmsPerioperative PeriodClinical recommendationImmune checkpoint inhibitor related adverse eventsLung neoplasmsPerioperative immunotherapy

Identifiers

PMID33819964
PMCPMC8143963
OpenAlexW3148904988

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.