Evidence map›Paper›PMID 33819949›Full record

ArticleNeurospine2021

Cement Augmentation of Vertebral Compression Fractures May Be Safely Considered in the Very Elderly.

Anoop R Galivanche, Courtney Toombs, Murillo Adrados, Wyatt B David, Rohil Malpani, Comron Saifi, Peter G Whang, Jonathan N Grauer, Arya G Varthi

Open access · diamondAbstract read
In one paragraph

Article in Neurospine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Anoop R GalivancheDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Courtney ToombsDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Murillo AdradosDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Wyatt B DavidDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Rohil MalpaniDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Comron SaifiPenn Orthopaedics, University of Pennsylvania, Philadelphia, PA, USA.
Peter G WhangDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Jonathan N GrauerDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Arya G VarthiDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Yale University · USUniversity of Pennsylvania · US

Funding

Short-Term Reserch Training: Students in Health SchoolsT35HL007649 · NHLBI · YALE UNIVERSITY · PI Sarwat I Chaudhry, Erica L Herzog · 1987 to 2026
$5.7M
NIA Short Term Research Training: Students in Health Professional SchoolsT35AG049685 · NIA · YALE UNIVERSITY · PI Sarwat I Chaudhry, Terri R. Fried · 2016 to 2026
$804k
NHLBI NIH HHS T35 HL007649NIA NIH HHS T35 AG049685NIH HHS T35AG049685
6 · The paper itself

Abstract

objectiveThe objective of the current study was to perform a retrospective review of a national database to assess the safety of cement augmentation for vertebral compression fractures in geriatric populations in varying age categories.

methodsThe 2005-2016 National Surgical Quality Improvement Program databases were queried to identify patients undergoing kyphoplasty or vertebroplasty in the following age categories: 60-69, 70-79, 80-89, and 90+ years old. Demographic variables, comorbidity status, procedure type, provider specialty, inpatient/outpatient status, number of procedure levels, and periprocedure complications were compared between age categories using chi-square analysis. Multivariate logistic regressions controlling for patient and procedural variables were then performed to assess the relative periprocedure risks of adverse outcomes of patients in the different age categories relative to those who were 60-69 years old.

resultsFor the 60-69, 70-79, 80-89, and 90+ years old cohorts, 486, 822, 937, and 215 patients were identified, respectively. After controlling for patient and procedural variables, 30-day any adverse events, serious adverse events, reoperation, readmission, and mortality were not different for the respective age categories. Cases in the 80- to 89-year-old cohort were at increased risk of minor adverse events compared to cases in the 60- to 69-year-old cohort.

conclusionAs the population ages, cement augmentation is being considered as a treatment for vertebral compression fractures in increasingly older patients. These results suggest that even the very elderly may be appropriately considered for these procedures (level of evidence: 3).

Indexed as

ElderlyGeriatricsKyphoplastyNonagenarianVertebroplasty

Identifiers

PMID33819949
PMCPMC8021820
OpenAlexW3145081770

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.