Evidence map›Paper›PMID 33819902›Full record

ArticleBiosensors & bioelectronics2021

Development strategies of conducting polymer-based electrochemical biosensors for virus biomarkers: Potential for rapid COVID-19 detection.

Vinh Van Tran, Nhu Hoa Thi Tran, Hye Suk Hwang, Mincheol Chang

Open access · greenAbstract read
In one paragraph

Article in Biosensors & bioelectronics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 98 citations in OpenAlex.

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  10. Batteryless wireless magnetostrictive FeSensors and actuators. A, Physical · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Vinh Van TranAlan G. MacDiarmid Energy Research Institute, Chonnam National University, Gwangju 61186, South Korea.
Nhu Hoa Thi TranFaculty of Materials Science and Technology, University of Science, HoChiMinh City 700000, Viet Nam; Vietnam National University, HoChiMinh City 700000, Viet Nam.
Hye Suk HwangAlan G. MacDiarmid Energy Research Institute, Chonnam National University, Gwangju 61186, South Korea. Electronic address: hshwang33@chonnam.ac.kr.
Mincheol ChangAlan G. MacDiarmid Energy Research Institute, Chonnam National University, Gwangju 61186, South Korea; Department of Polymer Engineering, Graduate School, Chonnam National University, Gwangju 61186, South Korea; School of Polymer Science and Engineering, Chonnam National University, Gwangju 61186, South Korea. Electronic address: mchang35@chonnam.ac.kr.
Chonnam National University · KRVietnam National University Ho Chi Minh City · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid, accurate, portable, and large-scale diagnostic technologies for the detection of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) are crucial for controlling the coronavirus disease (COVID-19). The current standard technologies, i.e., reverse-transcription polymerase chain reaction, serological assays, and computed tomography (CT) exhibit practical limitations and challenges in case of massive and rapid testing. Biosensors, particularly electrochemical conducting polymer (CP)-based biosensors, are considered as potential alternatives owing to their large advantages such as high selectivity and sensitivity, rapid detection, low cost, simplicity, flexibility, long self-life, and ease of use. Therefore, CP-based biosensors can serve as multisensors, mobile biosensors, and wearable biosensors, facilitating the development of point-of-care (POC) systems and home-use biosensors for COVID-19 detection. However, the application of these biosensors for COVID-19 entails several challenges related to their degradation, low crystallinity, charge transport properties, and weak interaction with biomarkers. To overcome these problems, this study provides scientific evidence for the potential applications of CP-based electrochemical biosensors in COVID-19 detection based on their applications for the detection of various biomarkers such as DNA/RNA, proteins, whole viruses, and antigens. We then propose promising strategies for the development of CP-based electrochemical biosensors for COVID-19 detection.

Indexed as

Biosensing TechniquesElectrochemical TechniquesBiomarkersCOVID-19HumansPolymersSARS-CoV-2BiomarkersPolymersConducting polymerCOVID-19Electrochemical biosensorImmuno-sensorSARS-CoV-2

Identifiers

PMID33819902
PMCPMC7992312
OpenAlexW3138783217

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.