ArticleThe Journal of steroid biochemistry and molecular biology2021
Differential effects of dietary cholesterol and triglycerides on the lipid homeostasis in Meibomian glands.
Article in The Journal of steroid biochemistry and molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Visibility-Graph Analysis of Raman Spectra in Chalazion and Lipid Dysregulation: An Exploratory Study.Entropy (Basel, Switzerland) · 2026Article
- Human meibomian gland organoids to study epithelial homeostasis and dysfunction.Protein & cell · 2026Article
- HDL May Improve Ocular Tear Film Stability in Patients with Gastric Bypass: A Pilot Study.Diagnostics (Basel, Switzerland) · 2025Article
- Comparative Analysis of Age-Associated Changes in Meibum Composition, Distribution, and Function in Mice With Altered Hyaluronan Expression.Investigative ophthalmology & visual science · 2025Article
- Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis.Communications biology · 2023Article
- Primary cilia control cellular patterning of Meibomian glands during morphogenesis but not lipid composition.Communications biology · 2023Article
- Dyslipidemia Exacerbates Meibomian Gland Dysfunction: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Dynamic Changes in the Gene Expression Patterns and Lipid Profiles in the Developing and Maturing Meibomian Glands.International journal of molecular sciences · 2022Article
- Effects of Aging on Human Meibum.Investigative ophthalmology & visual science · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Exocrine Meibomian glands (MG) play a central role in the ocular surface physiology by producing meibum - a lipid secretion composed of cholesteryl esters (CE), cholesterol (Chl), triacylgycerols (TAG), waxes and other types of lipids. MG were previously shown to synthesize Meibomian lipids (ML) in situ via a complex array of reactions termed meibogenesis. However, questions remain about the role of dietary lipids in meibogenesis. To establish if dietary Chl (DC) and TAG (DT) can participate in meibogenesis, we studied mice whose diet was supplemented with trace amounts of deuterated Chl (
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Registered trials
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