Trial reportAnnals of internal medicine2021
Preventing Hospital Readmission for Patients With Comorbid Substance Use Disorder : A Randomized Trial.
Trial report in Annals of internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 63 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Navigation Services to Avoid Rehospitalization (NavSTAR) Among Substance Users
Implementing a Patient Navigation Intervention Across a Health System to Address Treatment Entry Inequities
Implementing a Patient Navigation Intervention Across a Health System to Improve Outcomes for Patients With Opioid Use Disorder
Who cites it
63 citing papers in PubMed, 4 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Community care navigation intervention for people who are at risk of unplanned hospital presentations.The Cochrane database of systematic reviews · 2025Pooled it
- Substance Use Disorder Treatment Outcomes: Methodological Overview of Metrics and Criteria.International journal of methods in psychiatric research · 2025Pooled it
- Health-promotion interventions targeting multiple behaviors: A meta-analytic review of general and behavior-specific processes of change.Psychological bulletin · 2024Pooled it
- Post-hospitalization Care Transition Strategies for Patients with Substance Use Disorders: A Narrative Review and Taxonomy.Journal of general internal medicine · 2024Pooled it
- Addiction Consult Services, Mortality, and Acute Care Utilization in Inpatients With Opioid Use Disorder: A Secondary Analysis of a Cluster Randomized Clinical Trial.JAMA network open · 2025Trial
- Hospital admissions among patients with Comorbid Substance Use disorders: a secondary analysis of predictors from the NavSTAR Trial.Addiction science & clinical practice · 2024Trial
- Contextual barriers and enablers to establishing an addiction-focused consultation team for hospitalized adults with opioid use disorder.Addiction science & clinical practice · 2024Trial
- Hazardous Drinking Interventions Delivered During Medical-Surgical Care: Patient and Provider Views.Journal of clinical psychology in medical settings · 2024Trial
- Effect of a Co-Located Bridging Recovery Initiative on Hospital Length of Stay Among Patients With Opioid Use Disorder: The BRIDGE Randomized Clinical Trial.JAMA network open · 2024Trial
- Pilot randomized controlled trial of a hospital-based substance use treatment and recovery team (START) to improve initiation of medication for alcohol or opioid use disorder and linkage to follow-up care.Journal of substance use and addiction treatment · 2023Trial
- Cost and Cost Savings of Navigation Services to Avoid Rehospitalization for a Comorbid Substance Use Disorder Population.Medical care · 2022Trial
- The Emergency Department Longitudinal Integrated Care (ED-LINC) intervention targeting opioid use disorder: A pilot randomized clinical trial.Journal of substance abuse treatment · 2022Trial
- Preventability of Seven-Day Hospital Readmissions: A Structured Chart Review.Journal of general internal medicine · 2026Article
- Approaches to Collect Comprehensive Electronic Patient Data Across Multiple Providers and Payers for Research: Landscape Analysis.Journal of medical Internet research · 2026Article
- Patient Navigation With Hospital Addiction Consultation and Patient-Directed Discharge: Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2026Article
- "They Never, Never, Never Give Up on Me": Perspectives on an Addiction Consult Service From Hospitalized People Who Use Opioids at 6 New York City Public Hospitals.Substance use & addiction journal · 2026Article
- Integrated infectious disease and substance use disorder treatment for severe injection-related infections: protocol for the randomized controlled HI-SIRI trial.Addiction science & clinical practice · 2026Article
- A Peer-Led, Narrative-Based, and Mobile-Supported Intervention in Opioid Use Disorder: Multiphase Qualitative and Longitudinal Observational Study.JMIR formative research · 2026Observational
- Outcomes associated with an inpatient addiction consult service: Systematic review and meta-analysis.SAGE open medicine · 2026Review
- Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundHospitalized patients with comorbid substance use disorders (SUDs) are at high risk for poor outcomes, including readmission and emergency department (ED) use.
objectiveTo determine whether patient navigation services reduce hospital readmissions.
designRandomized controlled trial comparing Navigation Services to Avoid Rehospitalization (NavSTAR) versus treatment as usual (TAU). (ClinicalTrials.gov: NCT02599818).
settingUrban academic hospital in Baltimore, Maryland, with an SUD consultation service.
participants400 hospitalized adults with comorbid SUD (opioid, cocaine, or alcohol).
interventionNavSTAR used proactive case management, advocacy, service linkage, and motivational support to resolve internal and external barriers to care and address SUD, medical, and basic needs for 3 months after discharge. MEASUREMENTS: Data on inpatient readmissions (primary outcome) and ED visits for 12 months were obtained for all participants via the regional health information exchange. Entry into SUD treatment, substance use, and related outcomes were assessed at 3-, 6-, and 12-month follow-up.
resultsParticipants had high levels of acute care use: 69% had an inpatient readmission and 79% visited the ED over the 12-month observation period. Event rates per 1000 person-days were 6.05 (NavSTAR) versus 8.13 (TAU) for inpatient admissions (hazard ratio, 0.74 [95% CI, 0.58 to 0.96]; LIMITATION: Single-site trial, which limits generalizability.
conclusionPatient navigation reduced inpatient readmissions and ED visits in this clinically challenging sample of hospitalized patients with comorbid SUDs. PRIMARY FUNDING SOURCE: National Institute on Drug Abuse.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.