Evidence map›Paper›PMID 33818914›Full record

ArticleAndrology2021

Ultrasound aspects of symptomatic versus asymptomatic forms of male accessory gland inflammation.

Sandro La Vignera, Andrea Crafa, Rosita A Condorelli, Federica Barbagallo, Laura M Mongioì, Rossella Cannarella, Michele Compagnone, Antonio Aversa, Aldo E Calogero

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Andrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sandro La VigneraDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.ORCID 0000-0002-7113-2372
Andrea CrafaDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Rosita A CondorelliDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Federica BarbagalloDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Laura M MongioìDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.ORCID 0000-0003-2341-0996
Rossella CannarellaDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.ORCID 0000-0003-4599-8487
Michele CompagnoneDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Antonio AversaDepartment of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Catanzaro, Italy.ORCID 0000-0002-2989-2618
Aldo E CalogeroDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.ORCID 0000-0001-6950-335X
University of Catania · ITMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ultrasound (US) evaluation of the male sex accessory gland inflammation (MAGI) helps the clinicians to understand the severity of this condition, allowing them to distinguish the uncomplicated form (prostatitis) from the complicated ones (prostate-vesiculitis and prostate-vesiculitis-epididymitis), as well as the unilateral from the bilateral forms, the fibrosclerotic and the hypertrophic-congestive form.

objectiveThis retrospective study aimed to evaluate the US features of MAGI patients with active symptoms compared to patients without sexual, voiding, and ejaculatory dysfunction. MATERIALS/

methodsTo achieve this aim, an analysis of the prevalence of MAGI US criteria was carried out on a very large series of over 500 patients diagnosed with MAGI classified according to the different symptom profile evaluated through a dedicated questionnaire (previously conceived and published by our group) arbitrarily named "structured interview about MAGI" (SI-MAGI) for sexual, voiding, and ejaculatory disorders reported by these patients.

resultsThe results of this study revealed that US criteria most frequently detected in patients with severe urinary symptoms were the presence of areas of high echogenicity (almost exclusively in the periurethral prostatic zone) together with the presence of single or multiple areas of acinar ectasia of the prostate. The presence of seminal vesicles with polycyclic areas within the glandular lumen separated by hyperechoic septa represented US criterion most frequently detected in patients with severe spontaneous or post-ejaculate pain. Finally, US criterion most frequently detected in patients with severe sexual dysfunction was the dilation of the periprostatic venous plexus, suggesting the hypothesis of a possible alternative therapeutic approach.

conclusionThe data of the present study suggest that symptoms may associate with US signs in patients with MAGI. Also, specific US signs may associate with specific symptoms. Further studies are needed to understand whether patients with specific US signs may in turn benefit from a personalized therapeutic choice.

Indexed as

UltrasonographyAdultAsymptomatic DiseasesDiagnosis, DifferentialGenital Diseases, MaleGenitalia, MaleHumansInflammationMaleRetrospective StudiesSymptom AssessmentYoung Adultejaculatory disorderserectile dysfunctionMAGIquestionnairesymptomsultrasound

Identifiers

PMID33818914
PMCPMC8596874
OpenAlexW3148347235

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.