Evidence map›Paper›PMID 33818633›Full record

ArticleEuropean journal of nutrition2021

Dietary calcium, vitamin D, and breast cancer risk in women: findings from the SUN cohort.

Cesar I Fernandez-Lazaro, Andrea Romanos-Nanclares, Rodrigo Sánchez-Bayona, Alfredo Gea, Carmen Sayon-Orea, Miguel A Martinez-Gonzalez, Estefanía Toledo

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Cesar I Fernandez-LazaroDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, C/Irunlarrea, 31008, Pamplona, Spain.
Andrea Romanos-NanclaresDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, C/Irunlarrea, 31008, Pamplona, Spain.
Rodrigo Sánchez-BayonaDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, C/Irunlarrea, 31008, Pamplona, Spain.
Alfredo GeaDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, C/Irunlarrea, 31008, Pamplona, Spain.
Carmen Sayon-OreaDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, C/Irunlarrea, 31008, Pamplona, Spain.
Miguel A Martinez-GonzalezDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, C/Irunlarrea, 31008, Pamplona, Spain.
Estefanía ToledoDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, C/Irunlarrea, 31008, Pamplona, Spain. etoledo@unav.es.ORCID http://orcid.org/0000-0002-6263-4434
Navarre Institute of Health Research · ESClinica Universidad de Navarra · ESHarvard University · USInstituto de Salud Pública de Navarra · ES

Funding

European Regional Development Fund RD 06/0045Instituto de Salud Carlos III CIBER-OBNInstituto de Salud Carlos III G03/140Instituto de Salud Carlos III Grants PI10/02658Instituto de Salud Carlos III PI10/02293Instituto de Salud Carlos III PI13/00615Instituto de Salud Carlos III PI14/01668Instituto de Salud Carlos III PI14/01764Instituto de Salud Carlos III PI14/01798Instituto de Salud Carlos III PI17/01795Navarra Regional Government 122/2014Navarra Regional Government 41/2016Navarra Regional Government 45/2011
6 · The paper itself

Abstract

purposeEpidemiological evidence concerning the relationship between calcium and vitamin D intake and breast cancer (BC) is inconclusive. Moreover, the association according to menopausal status remains unclear. We aimed to assess whether total intakes from dietary and supplemental sources of calcium and vitamin D were associated with the incidence of BC in a Mediterranean cohort.

methodsWe prospectively evaluated the association between intakes of calcium and vitamin D and BC risk among 10,812 women in the Seguimiento Universidad de Navarra (SUN) Project, a Spanish cohort of university graduates.

resultsDuring a mean follow-up of 10.7 years, 101 incident BC cases were confirmed. Evidence of a non-linear association between total calcium intake and BC risk was found (P

conclusionsOur findings suggest an L-shaped association between total calcium intake and BC incidence. Moderate calcium intake may be associated with lower BC risk among overall and postmenopausal women, but not among premenopausal women. No evidence for any association between vitamin D intake and BC was found. Adherence to current guidelines recommendations for calcium intake may help to reduce BC risk.

Indexed as

Breast NeoplasmsCalcium, DietaryCohort StudiesFemaleHumansProspective StudiesRisk FactorsVitamin DCalcium, DietaryVitamin DBreast cancerCalciumChemopreventionMediterranean cohortSUN studyVitamin D

Identifiers

PMID33818633
OpenAlexW3140629668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.