Evidence map›Paper›PMID 33818010›Full record

ArticleOrthopaedic surgery2021

Risk Factors and Outcomes for Preoperative Asymptomatic Pulmonary Embolism in Patients Aged 60 Years and Over with Hip Fracture.

Fang-Lun Zhou, Li-Hong Wang, Cheng-Qian Dai, Guo-Jian Shentu, Guo-Hong Xu

Open access · goldAbstract read
In one paragraph

Article in Orthopaedic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Pulmonary Embolism in Women: A Systematic Review of the Current Literature.Journal of cardiovascular development and disease · 2022
    Review
  9. Review
  10. Low Mean Platelet Volume is Associated with Deep Vein Thrombosis in Older Patients with Hip Fracture.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fang-Lun ZhouDepartment of Arthrology, Dongyang People's Hospital, Wenzhou Medical University Affiliated Dongyang Hospital, Dongyang, China.ORCID https://orcid.org/0000-0003-3753-2708
Li-Hong WangDepartment of Arthrology, Dongyang People's Hospital, Wenzhou Medical University Affiliated Dongyang Hospital, Dongyang, China.ORCID https://orcid.org/0000-0002-4404-8589
Cheng-Qian DaiDepartment of Arthrology, Dongyang People's Hospital, Wenzhou Medical University Affiliated Dongyang Hospital, Dongyang, China.ORCID https://orcid.org/0000-0001-5759-3415
Guo-Jian ShentuDepartment of Arthrology, Dongyang People's Hospital, Wenzhou Medical University Affiliated Dongyang Hospital, Dongyang, China.ORCID https://orcid.org/0000-0002-5983-0354
Guo-Hong XuDepartment of Arthrology, Dongyang People's Hospital, Wenzhou Medical University Affiliated Dongyang Hospital, Dongyang, China.ORCID https://orcid.org/0000-0002-9279-8093
Wenzhou Medical University · CN

Funding

Health Commission of Zhejiang Province 2018KY864
6 · The paper itself

Abstract

objectiveTo investigate the risk factors for, and outcomes of, preoperative asymptomatic pulmonary embolism (PE) in patients ≥60 years old following delayed operation for hip fracture.

methodsFrom March 2017 to December 2018, 90 patients aged ≥60 years with hip fracture who suffered a delay in surgery were recruited to this prospective study following admission to our hospital. Computed tomography pulmonary angiography (CTPA) was used to detect preoperative asymptomatic PE and calculated its incidence. Time from injury to admission, baseline characteristics, medical comorbidities, and blood biomarker levels were evaluated as potential risk factors. Logistic regression analysis was used to identify risk factors. Mortality and major bleeding events were recorded and compared between individuals with PE and without. Data were analyzed by t-test, Mann-Whitney U test, χ

resultsThe incidence of preoperative asymptomatic PE was 18.9% (17/90 patients). In the univariate analysis, the risk factors for preoperative asymptomatic PE were male sex, hypertension, cerebrovascular accident, smoking, plasma D-dimer level, potassium level, urea level, creatinine level, and cysteine level. Multivariate logistic regression analysis showed that the risk of preoperative asymptomatic PE was higher in patients with hypertension (odds ratio [OR] = 10.048; 95% confidence interval [CI], 1.118-90.333), cerebrovascular accident (OR = 20.135; 95% CI, 1.875-216.164), smoking (OR = 48.741; 95% CI, 4.155-571.788), high plasma D-dimer levels (OR = 1.200; 95% CI, 1.062-157.300), and high plasma potassium levels (OR = 12.928; 95% CI, 1.062-157.300). All patients were followed up for 21.0 months (range, 2 to 36 months). Mortality within the first year postoperatively was higher in patients with PE (29.41% vs 9.59%, P = 0.046).

conclusionsIn view of the high incidence of preoperative asymptomatic PE and the inferior prognosis in individuals with PE, routine CTPA examination for preoperative asymptomatic PE could be useful for patients aged ≥60 years with hip fracture for whom surgery is delayed.

Indexed as

AgedAged, 80 and overAsymptomatic DiseasesBiomarkersFemaleHip FracturesHumansIncidenceMaleMiddle AgedPreoperative PeriodProspective StudiesPulmonary EmbolismRisk FactorsTime-to-TreatmentBiomarkersHip fracturesPreoperativePulmonary embolism

Identifiers

PMID33818010
PMCPMC8126953
OpenAlexW3146369628

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.