Evidence map›Paper›PMID 33818006›Full record

Trial reportPhysiological reports2021

Effect of treatment of peripheral arterial disease on the onset of anaerobic exercise during cardiopulmonary exercise testing.

Mohamed Barkat, Angela Key, Tamara Ali, Paul Walker, Nick Duffy, Jayne Snellgrove, Francesco Torella

2 registry-linked trialsOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02657278 nacompletednot on this map

The Influence of Peripheral Arterial Disease (PAD) on the Onset of Lactate Threshold (LT) in Patients Undergoing Cardiopulmonary Exercise Test (CPET)

TypeinterventionalSponsorLiverpool University Hospitals NHS Foundation TrustRan2016 to 2017Enrolled31ConditionsPeripheral Arterial DiseaseArmsArterial Revascularization surgery or Endovascular procedure
NCT05861089 completednot on this mapstarted 2023, after this paper: background citation

Rest PETCO2 as a Predictor of Post-operative Complications in Patient Undergoing Major Vascular Surgery

TypeobservationalSponsorSt. Anne's University Hospital Brno, Czech RepublicRan2023 to 2026Enrolled91ConditionsPost-Op ComplicationArmsend-tidal CO2 measurement
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mohamed BarkatLiverpool Vascular and Endovascular Service, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Angela KeyDepartment of Respiratory Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Tamara AliFaculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.
Paul WalkerDepartment of Respiratory Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Nick DuffyDepartment of Respiratory Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Jayne SnellgroveLiverpool Vascular and Endovascular Service, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Francesco TorellaLiverpool Vascular and Endovascular Service, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.ORCID 0000-0003-0529-7387
University of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCardiopulmonary exercise testing (CPET) is often used to assess pre-operative fitness in elderly patients, in whom peripheral arterial disease (PAD) is highly prevalent, but may affect the results of CPET by early lactate release due to muscle ischemia. This study investigated the effect revascularization of PAD on oxygen delivery (VO

methodWe conducted a prospective cohort study of 30 patients, who underwent CPET before and after treatment of ilio-femoral PAD. The primary outcome measure was difference in VO

resultsThe study was approved by the North West-Lancaster Research and Ethics committee (reference 15/NW/0801) and registered in clinicaltrial.gov (reference NCT02657278). As specified in the study protocol, 30 patients were recruited but only 20 (15 men), with a mean age of 62 years, completed pre- and post-treatment CPETs. Twelve patients demonstrated an improvement in VO

conclusionRevascularization of PAD led to significant improvement in multiple peak/maximal exercise parameters within a few weeks and without exercise training. We were unable to demonstrate a statistically significant improvement in VO

Indexed as

Anaerobic ThresholdAgedExercise TestFemaleHumansMaleMiddle AgedMuscle, SkeletalPeripheral Arterial DiseasePostoperative ComplicationsVascular Surgical Proceduresaerobic thresholdatherosclerosisskeletal muscle

Identifiers

PMID33818006
PMCPMC8020047
OpenAlexW3144940976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.