ReviewCurrent neurology and neuroscience reports2021
Functional Connectome in Parkinson's Disease and Parkinsonism.
Review in Current neurology and neuroscience reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 36 citations in OpenAlex.
- Temporal Interference Stimulation Modulates Resting State Functional Connectivity of Motor Circuit in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026Trial
- A review of FDG-PET biomarker analysis methods in Parkinson's disease.Journal of Parkinson's disease · 2026Review
- Harmonized Acquisition of Connectome MRI and Clinical Data for Stroke, Parkinson's Disease and Glioma: Delphi-Derived Protocol Recommendations by the European Academy of Neurology.European journal of neurology · 2026Review
- Pallidal and subthalamic stimulations modulate inter-hemispheric interaction and asymmetry in Parkinson's disease.Molecular psychiatry · 2026Article
- Characteristics and mechanisms of cognitive impairment in Parkinson disease.Nature reviews. Neurology · 2026Review
- Comparative effects of medication combined with twenty rehabilitation therapies: core outcomes in 8202 parkinson's patients.NPJ Parkinson's disease · 2026Article
- A Cross Sectional and Longitudinal Assessment of Neuropsychiatric Symptoms and Brain Functional Connectivity in Patients With Mild Cognitive Impairment, Cerebrovascular Disease and Parkinson Disease.International journal of geriatric psychiatry · 2025Article
- Resting-State Functional MRI Approaches to Parkinsonisms and Related Dementia.Current neurology and neuroscience reports · 2024Review
- Role of the central nervous system in cell non-autonomous signaling mechanisms of aging and longevity in mammals.The journal of physiological sciences : JPS · 2024Review
- Review of the Brain's Behaviour after Injury and Disease for Its Application in an Agent-Based Model (ABM).Biomimetics (Basel, Switzerland) · 2024Review
- Resting-state EEG dynamic functional connectivity distinguishes non-psychotic major depression, psychotic major depression and schizophrenia.Molecular psychiatry · 2024Article
- Normalization effect of dopamine replacement therapy on brain functional connectome in Parkinson's disease.Human brain mapping · 2023Article
- The evolution of Big Data in neuroscience and neurology.Journal of big data · 2023Article
- Continuous theta burst stimulation over right cerebellum for speech impairment in Parkinson's disease: study protocol for a randomized, sham-controlled, clinical trial.Frontiers in aging neuroscience · 2023Article
- Functional connectivity of the cortico-subcortical sensorimotor loop is modulated by the severity of nigrostriatal dopaminergic denervation in Parkinson's Disease.NPJ Parkinson's disease · 2022Article
- Multiple system atrophy.Nature reviews. Disease primers · 2022Review
- Characterization of Early Stage Parkinson's Disease From Resting-State fMRI Data Using a Long Short-Term Memory Network.Frontiers in neuroimaging · 2022Article
- Deep Brain Stimulation Modulates Multiple Abnormal Resting-State Network Connectivity in Patients With Parkinson's Disease.Frontiers in aging neuroscience · 2022Article
- The Parkinson disease connectome - insights from new imaging studies.Nature reviews. Neurology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
purpose of reviewThere has been an exponential growth in functional connectomics research in neurodegenerative disorders. This review summarizes the recent findings and limitations of the field in Parkinson's disease (PD) and atypical parkinsonian syndromes. RECENT
findingsIncreasingly more sophisticated methods ranging from seed-based to network and whole-brain dynamic functional connectivity have been used. Results regarding the disruption in the functional connectome vary considerably based on disease severity and phenotypes, and treatment status in PD. Non-motor symptoms of PD also link to the dysfunction in heterogeneous networks. Studies in atypical parkinsonian syndromes are relatively scarce. An important clinical goal of functional connectomics in neurodegenerative disorders is to establish the presence of pathology, track disease progression, predict outcomes, and monitor treatment response. The obstacles of reliability and reproducibility in the field need to be addressed to improve the potential of the functional connectome as a biomarker for these purposes in PD and atypical parkinsonian syndromes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.