Evidence map›Paper›PMID 33817707›Full record

ArticleRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie

The role of mediating factors involved in angiogenesis during implantation.

Lidia Boldeanu, Anda Lorena Dijmărescu, Mirela Radu, Cristian Adrian Siloşi, Mircea Vasile Popescu-Drigă, Ioan Sabin Poenariu, Isabela Siloşi, Mihail Virgil Boldeanu, Marius Bogdan Novac, Liliana Victoria Novac

Open access · diamondAbstract read
In one paragraph

Article in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  13. Analysis of the relationship between placental histopathological aspects of preterm and term birth.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
  14. The potential value of diagnostic and predictive serum biomarkers for preeclampsia.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lidia BoldeanuDepartment of Immunology, Department of Anesthesiology and Intensive Care, University of Medicine and Pharmacy of Craiova, Romania; boldeanumihailvirgil@yahoo.com, mihail.boldeanu@umfcv.ro, mariusnovac2005@yahoo.com.
Anda Lorena Dijmărescu
Mirela Radu
Cristian Adrian Siloşi
Mircea Vasile Popescu-Drigă
Ioan Sabin Poenariu
Isabela Siloşi
Mihail Virgil Boldeanu
Marius Bogdan Novac
Liliana Victoria Novac
University of Medicine and Pharmacy of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenesis is a critical component of normal implantation and placentation and underlines the importance of vascularization in early pregnancy. Differentiated expression of angiogenesis factors in different decision tissues during different stages of implantation, indicates their involvement in the regulation of vascular remodeling and angiogenesis. Disorders in vascular development may play a role in the pathogenesis of recurrent abortions. The success of implantation, placentation and subsequent pregnancy evolution requires coordination of vascular development and adaptations at both sides of the maternal-fetal interface. The human implantation process is a continuous process, which begins with the apposition and attachment of the blastocyst to the apical surface of the luminal endometrial epithelium and continues throughout the first trimester of pregnancy until the extravillous trophoblast invades and remodels maternal vascularization. Numerous regulatory molecules play functional roles in many processes, including preparation of the endometrial stroma (decidualization), epithelium for implantation, control of trophoblastic adhesion and invasion. These regulatory molecules include cytokines, chemokines, and proteases, many of which are expressed by different cell types, having slightly different functions as the implant progresses.

Indexed as

Embryo ImplantationMediation AnalysisEndometriumFemaleHumansPlacentationPregnancyTrophoblasts

Identifiers

PMID33817707
PMCPMC8112745
OpenAlexW3143453157

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.