Evidence map›Paper›PMID 33817705›Full record

ReviewRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie

Global hepatitis C elimination: history, evolution, revolutionary changes and barriers to overcome.

Carmen Nicoleta Oancea, Anca Elena Butaru, Costin Teodor Streba, Daniel Pirici, Ion Rogoveanu, Mihai Mircea Diculescu, Dan Ionuţ Gheonea

Open access · diamondAbstract readReview
In one paragraph

Review in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Prevalence, trends, and distribution of hepatitis C virus among the general population in sub-Saharan Africa: A systematic review and meta-analysis.Liver international : official journal of the International Association for the Study of the Liver · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Comparison of AmpliSens® HCV genotype-FRT-g-1-6 PCR kit with Abbott® Real Time HCV genotype II assay for hepatitis C virus genotyping.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Article
  7. Antivirals in COVID-19: A Focus on Pediatric Cardiac Patients.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. The differential diagnosis of ulcerative colitis versus angiodysplasia of the colon with ischemic colitis.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
  14. Article
  15. Hepatic injuries resulting from chronic alcohol abuse identified by forensics.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
  16. Diagnostic and prognostic significance of hepatic steatosis in patients with chronic hepatitis C.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Carmen Nicoleta OanceaDepartment of Scientific Research Methodology and Department of Pulmonology, University of Medicine and Pharmacy of Craiova, Romania; costin.streba@umfcv.ro.
Anca Elena Butaru
Costin Teodor Streba
Daniel Pirici
Ion Rogoveanu
Mihai Mircea Diculescu
Dan Ionuţ Gheonea
University of Medicine and Pharmacy of Craiova · ROCarol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fundamental discovery of the hepatitis C virus (HCV) in 1989 has led to winning this year's Nobel Prize in Medicine. This achievement guided all the steps in identifying the elements of the virus, in order to develop the treatment and to increase the screening solutions, which have slowed the exposure to the virus. The management of infection started with interferon-alpha (IFN-α), which has later enhanced by adding Ribavirin. Nowadays, HCV treatment is based on direct-acting antiviral agents (DAAs). Currently, HCV infection benefits of curative treatment, with which most patients can be cured. When speaking about hepatitis C future, we can say it is looking bright, considering all the progress that has been made in recent years and all the options that we have for curing all genotypes of HCV infection. The aim of this review is to sum up the historical characteristics of HCV discovery, the evolution of treatment and screening actions, gaps, and stages for achieving the international elimination target of the World Health Organization.

Indexed as

Hepatitis CHepatitis C, ChronicAntiviral AgentsHepacivirusHumansRibavirinAntiviral AgentsRibavirin

Identifiers

PMID33817705
PMCPMC8112794
OpenAlexW3143156448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.