Evidence map›Paper›PMID 33817509›Full record

ArticleACS omega2021

Synthetic Derivatives of Ciclopirox are Effective Inhibitors of

Jeffrey Lin, Maryam Zangi, Tanguturi Venkata Narayana Hajay Kumar, Makala Shakar Reddy, Lingala Vijaya Raghava Reddy, Subir Kumar Sadhukhan, Daniel P Bradley, Brenda Moreira-Walsh, Tiffany C Edwards, Austin T O'Dea and 3 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Antifungal Activity ofAntibiotics (Basel, Switzerland) · 2024
    Article
  6. Ferroptosis inhibitors: past, present and future.Frontiers in pharmacology · 2024
    Review
  7. Efficacy and non-toxicity of ciclopirox olamine-loaded liposomes against Cryptococcus neoformans clinical isolates.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jeffrey LinDepartment of Biology, Saint Louis University, 3507 Laclede Avenue, St. Louis, Missouri 63103, United States.
Maryam ZangiDepartment of Chemistry, Saint Louis University, 3501 Laclede Avenue, St. Louis, Missouri 63103, United States.
Tanguturi Venkata Narayana Hajay KumarMedicinal Chemistry Division, Albany Molecular Research Inc., MN Park, Turkpally Shamirpet Mandal, Genome Valley, Hyderabad 500078, India.
Makala Shakar ReddyMedicinal Chemistry Division, Albany Molecular Research Inc., MN Park, Turkpally Shamirpet Mandal, Genome Valley, Hyderabad 500078, India.
Lingala Vijaya Raghava ReddyMedicinal Chemistry Division, Albany Molecular Research Inc., MN Park, Turkpally Shamirpet Mandal, Genome Valley, Hyderabad 500078, India.
Subir Kumar SadhukhanMedicinal Chemistry Division, Albany Molecular Research Inc., MN Park, Turkpally Shamirpet Mandal, Genome Valley, Hyderabad 500078, India.
Daniel P BradleyDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, 1100 South Grand Blvd., St. Louis, Missouri 63104, United States.
Brenda Moreira-WalshEdward A. Doisy Department of Biochemistry, Saint Louis University School of Medicine, 1100 South Grand Blvd., St. Louis, Missouri 63104, United States.
Tiffany C EdwardsDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, 1100 South Grand Blvd., St. Louis, Missouri 63104, United States.
Austin T O'DeaDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, 1100 South Grand Blvd., St. Louis, Missouri 63104, United States.
John E TavisDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, 1100 South Grand Blvd., St. Louis, Missouri 63104, United States.
Marvin J MeyersDepartment of Chemistry, Saint Louis University, 3501 Laclede Avenue, St. Louis, Missouri 63103, United States.
Maureen J DonlinEdward A. Doisy Department of Biochemistry, Saint Louis University School of Medicine, 1100 South Grand Blvd., St. Louis, Missouri 63104, United States.
Saint Louis University · USAlbany Molecular Research (United States) · US

Funding

ROLE OF CELL WALL INTEGRITY IN ECHINOCANDIN RESISTANCE IN C. NEOFORMANSR01AI123407 · NIAID · WASHINGTON UNIVERSITY · PI DONLIN, MAUREEN J, LODGE, JENNIFER K. · 2017 to 2021
$1.9M
Nucleotidyl transferase antagonists as inhibitors of HSV replicationR21AI135311 · NIAID · SAINT LOUIS UNIVERSITY · PI MORRISON, LYNDA A. · 2018 to 2019
$417k
NIAID NIH HHS R01 AI123407NIAID NIH HHS R21 AI135311
6 · The paper itself

Abstract

Opportunistic fungal infections caused by

Identifiers

PMID33817509
PMCPMC8015083
OpenAlexW3138778100

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.