ArticleOpen life sciences2018
16S Ribosomal RNA-based Gut Microbiome Composition Analysis in Infants with Breast Milk Jaundice.
Article in Open life sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Breast Milk Constituents and the Development of Breast Milk Jaundice in Neonates: A Systematic Review.Nutrients · 2023Pooled it
- Altered gut microbiota and metabolites in children with non-organic anorexia: a multi-omics integration study.Scientific reports · 2026Article
- Impact of phototherapy on gut microbiota composition and function in neonates with hyperbilirubinemia: a metagenomic analysis.BMC pediatrics · 2026Article
- The enhancing therapeutic effect of neonatal jaundice byFrontiers in microbiology · 2026Article
- From Mother to Baby: The Role of Human Milk Vitamins in Infant Body Development and Breast Milk Jaundice-An Observational Study.Food science & nutrition · 2025Article
- Breast milk jaundice affects breastfeeding: From the perspective of intestinal flora and SCFAs-GPR41/43.Frontiers in nutrition · 2023Review
- Fatty acid profile driven by maternal diet is associated with the composition of human milk microbiota.Frontiers in microbiomes · 2022Article
- Association of Neonatal Jaundice with Gut Dysbiosis Characterized by Decreased Bifidobacteriales.Metabolites · 2021Article
- Deterministic transition of enterotypes shapes the infant gut microbiome at an early age.Genome biology · 2021Article
- Changes in Intestinal Flora and Metabolites in Neonates With Breast Milk Jaundice.Frontiers in pediatrics · 2020Article
- The role of microbiota in neonatal hyperbilirubinemia.American journal of translational research · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis case-control study investigated an association between breast milk jaundice (BMJ) and infants' gut microbiome. The study included determination of the diversity of the gut microbiome and identification of bacterial genera associated with BMJ.
methodsThe study population consisted of 12 infants with BMJ and 22 breastfed infants without jaundice (control). DNA collected from feces was analyzed by PCR amplification and 1% agarose gel electrophoresis, and then sequenced with a MiSeq system. Relative quantification bioinformatics was employed to analyze the DNA sequencing data. An Illumina high-throughput sequencing platform was used to analyze 16S rRNA variable (V) regions V3 and V4 in stool samples.
resultsIn the control group, the proportion of
conclusionThe prevalence of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.