ArticleOpen life sciences2018
Salivary Protein Roles in Oral Health and as Predictors of Caries Risk.
Article in Open life sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Role of Salivary Biomarkers in Cystic Fibrosis: A Systematic Review.BioMed research international · 2022Pooled it
- Obesity and Dental Caries: A State-of-the-Art Review of Shared Risk Factors, Biological Mechanisms and Current Evidence.Medical sciences (Basel, Switzerland) · 2026Review
- Salivary immune alteration persists after caries treatment.Scientific reports · 2026Article
- Investigation of the relationship between caries predisposition and salivary characteristics.European oral research · 2026Article
- Pre-post intervention changes in salivary biomarkers after dental treatment in children with caries: A systematic review and meta-analysis.Journal of clinical and experimental dentistry · 2025Review
- Article
- Acquired enamel pellicle and biofilm engineering with a combination of acid-resistant proteins (CaneCPI-5, StN15, and Hemoglobin) for enhanced protection against dental caries - in vivo and in vitro investigations.Clinical oral investigations · 2024Article
- Salivary alpha-amylase activity and its association with early childhood caries and rampant caries experience: a cross-sectional study.Frontiers in medicine · 2024Article
- Salivary Proteins and Metabolites as Caries Biomarkers in Adolescents.Caries research · 2024Article
- A Catalog of Coding Sequence Variations in Salivary Proteins' Genes Occurring during Recent Human Evolution.International journal of molecular sciences · 2023Article
- Association of polymicrobial interactions with dental caries development and prevention.Frontiers in microbiology · 2023Review
- Correlation Between BMI, Caries Prevalence, and Sugar-containing Beverage Intake in 6-10 Year Old Children.Journal of pharmacy & bioallied sciences · 2022Article
- Does Growth Stunting Correlate with Oral Health in Children?: A Systematic Review.European journal of dentistry · 2022Article
- Relationship between Salivary Alpha-Amylase Enzyme Activity, Anthropometric Indices, Dietary Habits, and Early Childhood Dental Caries.International journal of dentistry · 2022Article
- Antimicrobial peptides: Defending the mucosal epithelial barrier.Frontiers in oral health · 2022Review
- Review
- Current State and Challenges of the Global Outcomes of Dental Caries Research in the Meta-Omics Era.Frontiers in cellular and infection microbiology · 2022Review
- Salivary cystatin S levels in children with early childhood caries in comparison with caries-free children; statistical analysis and machine learning.BMC oral health · 2021Article
- Metabolomics to Diagnose Oxidative Stress in Perinatal Asphyxia: Towards a Non-Invasive Approach.Antioxidants (Basel, Switzerland) · 2021Review
- Impact ofJournal of oral biology and craniofacial researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work describes the current state of research on the potential relationship between protein content in human saliva and dental caries, which remains among the most common oral diseases and causes irreversible damage in the oral cavity. An understanding the whole saliva proteome in the oral cavity could serve as a prerequisite to obtaining insight into the etiology of tooth decay at early stages. To date, however, there is no comprehensive evidence showing that salivary proteins could serve as potential indicators for the early diagnosis of the risk factors causing dental caries. Therefore, proteomics indicates the promising direction of future investigations of such factors, including diagnosis and thus prevention in dental therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.