ArticlePeerJ. Computer science2020
HACSim: an R package to estimate intraspecific sample sizes for genetic diversity assessment using haplotype accumulation curves.
Article in PeerJ. Computer science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- PCR-based species identification tools for wireworms (Coleoptera: Elateridae) of economic importance in Canada.Pest management science · 2026Article
- Statistical Modeling of Seafood Fraud Highlights Uncertainties in Products From Metro Vancouver, British Columbia, Canada: Revisiting Hu et al. (2018).Journal of food science · 2026Article
- Trichomonas vaginalis strain diversity among female sex workers in Ecuador using DNA sequence-based typing.BMC infectious diseases · 2025Article
- Phylogeography of the Sunda pangolin,Ecology and evolution · 2023Article
- Article
- Genetic population dynamics of the critically endangered scalloped hammerhead shark (Ecology and evolution · 2022Article
- Opportunities and challenges of macrogenetic studies.Nature reviews. Genetics · 2021Review
- Genetic diversity of the Nubian ibex in Oman as revealed by mitochondrial DNA.Royal Society open science · 2021Article
- A DNA barcode-based survey of wild urban bees in the Loire Valley, France.Scientific reports · 2021Article
- Application of deep autoencoder as an one-class classifier for unsupervised network intrusion detection: a comparative evaluation.PeerJ. Computer science · 2020Article
Corrections and comments
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Assessing levels of standing genetic variation within species requires a robust sampling for the purpose of accurate specimen identification using molecular techniques such as DNA barcoding; however, statistical estimators for what constitutes a robust sample are currently lacking. Moreover, such estimates are needed because most species are currently represented by only one or a few sequences in existing databases, which can safely be assumed to be undersampled. Unfortunately, sample sizes of 5-10 specimens per species typically seen in DNA barcoding studies are often insufficient to adequately capture within-species genetic diversity. Here, we introduce a novel iterative extrapolation simulation algorithm of haplotype accumulation curves, called HACSim (
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