Evidence map›Paper›PMID 33816808›Full record

ArticlePeerJ. Computer science2018

Supervised deep learning embeddings for the prediction of cervical cancer diagnosis.

Kelwin Fernandes, Davide Chicco, Jaime S Cardoso, Jessica Fernandes

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PeerJ. Computer science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07215728 (Computational Analysis Using Machine Learning Algorithms of Electronic Medical Record Data From Patients With Osteosarcoma or Ewing's Sarcoma), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07215728 completednot on this map

Computational Analysis Using Machine Learning Algorithms of Electronic Medical Record Data From Patients With Osteosarcoma or Ewing's Sarcoma

TypeobservationalSponsorUniversity of Milano BicoccaRan2003 to 2012Enrolled700ConditionsSarcoma, Osteosarcoma, Ewing SarcomaArmsNo intervention studied
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. A Deep Clustering Method For Analyzing Uterine Cervix Images Across Imaging Devices.Proceedings. IEEE International Symposium on Computer-Based Medical Systems · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Artificial Intelligence in Pathology.Journal of pathology and translational medicine · 2019
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Kelwin FernandesInstituto de Engenharia de Sistemas e Computadores Tecnologia e Ciencia (INESC TEC), Porto, Portugal.ORCID 0000-0002-6838-9484
Davide ChiccoPrincess Margaret Cancer Centre, Toronto, ON, Canada.ORCID 0000-0001-9655-7142
Jaime S CardosoInstituto de Engenharia de Sistemas e Computadores Tecnologia e Ciencia (INESC TEC), Porto, Portugal.
Jessica FernandesUniversidad Central de Venezuela, Caracas, Venezuela.ORCID 0000-0002-9369-8983
Universidade do Porto · PTCentral University of Venezuela · VEPrincess Margaret Cancer Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer remains a significant cause of mortality all around the world, even if it can be prevented and cured by removing affected tissues in early stages. Providing universal and efficient access to cervical screening programs is a challenge that requires identifying vulnerable individuals in the population, among other steps. In this work, we present a computationally automated strategy for predicting the outcome of the patient biopsy, given risk patterns from individual medical records. We propose a machine learning technique that allows a joint and fully supervised optimization of dimensionality reduction and classification models. We also build a model able to highlight relevant properties in the low dimensional space, to ease the classification of patients. We instantiated the proposed approach with deep learning architectures, and achieved accurate prediction results (top area under the curve AUC = 0.6875) which outperform previously developed methods, such as denoising autoencoders. Additionally, we explored some clinical findings from the embedding spaces, and we validated them through the medical literature, making them reliable for physicians and biomedical researchers.

Indexed as

Artificial neural networksAutoencoderBinary classificationBiomedical informaticsCervical cancerDeep learningDenoising autoencoderDimensionality reductionHealth-care informaticsHealth informatics

Identifiers

PMID33816808
PMCPMC7924508
OpenAlexW2802494476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.