ArticleAmerican journal of clinical and experimental urology2021
Bladder wall micromotion measured by non-invasive ultrasound: initial results in women with and without overactive bladder.
Article in American journal of clinical and experimental urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Feasibility Study on Non-Invasive Methods for Bladder Biomechanics During Voiding Using Uro-Dynamic MRI.Bioengineering (Basel, Switzerland) · 2026Article
- Quantitative Mechanics of the Bladder During Voiding Using MRI.Neurourology and urodynamics · 2025Article
- Increased Afferent Nerve Firing Is Correlated With the Detection of Bladder Wall Micromotion in a Perfused Ex-Vivo Porcine Model.Neurourology and urodynamics · 2025Article
- New Imaging Techniques on the Horizon to Study Overactive and Neurogenic Bladder.Current bladder dysfunction reports · 2025Review
- Validation of Dynamic 3D MRI for Urodynamics Assessment Using an Anatomically Realistic In Vitro Model of the Bladder.Journal of biomechanical engineering · 2024Article
- Ultrasound Urodynamics: A Review of Ultrasound Imaging Techniques for Enhanced Bladder Functional Diagnostics.Current bladder dysfunction reports · 2024Review
- Irregular bladder shapes identified in women with overactive bladder: an ultrasound nomogram.American journal of clinical and experimental urology · 2021Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveRhythmic contractions of the bladder wall during filling result from the synchronization of bladder wall micromotion and are often observed in the urodynamic tracings of individuals with urinary overactive bladder (OAB). This study's objective was to develop a novel, non-invasive method to measure bladder wall micromotion and to conduct an initial study to test the hypothesis that elevated micromotion is associated with OAB.
methodsThis prospective study enrolled women with OAB and asymptomatic volunteers as measured by the ICIQ-OAB survey. After filling the bladder to 40% cystometric capacity, 85 second cine-loops were obtained using a GE Voluson E8 ultrasound system with an 8 MHz curved, abdominal probe. A custom correlation-based texture tracking MATLAB algorithm was used to measure changes in the bladder wall thickness over time and correlate with changes in vesical pressure. Significant bladder wall micromotion was defined as changes in wall thickness with amplitudes higher than 0.1 mm in the frequency range of 1.75-6 cycles/minute as calculated from Fast Fourier Transform (FFT) analysis. The micromotion algorithm was tested on 30 women including 17 with OAB and 13 asymptomatic volunteers.
resultsMicromotion was identified in 41% of subjects with OAB and 0% of asymptomatic volunteers, indicating a significant association of micromotion with OAB (Fisher's exact test, P=0.010). Micromotion was also found to have a significant association with a clinical diagnosis of detrusor overactivity (Fisher's exact test, P=0.031). Frequencies with elevated micromotion correlated with frequencies of vesical pressure fluctuations.
conclusionsThe feasibility of a non-invasive method to measure bladder wall micromotion was demonstrated using transabdominal anatomical motion mode (M-mode) ultrasound. Presence of micromotion was significantly associated with OAB and with urodynamic-identified rhythm.
Indexed as
Identifiers
33816693PMC8012835W3149714573What OpenQuestion holds
Registered trials
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