Evidence map›Paper›PMID 33816665›Full record

ArticleMovement disorders clinical practice2021

Exploring Interrater Disagreement on Essential Tremor Using a Standardized Tremor Elements Assessment.

Jos Becktepe, Felix Gövert, Bettina Balint, Christian Schlenstedt, Kailash Bhatia, Rodger Elble, Günther Deuschl

Abstract read
In one paragraph

Article in Movement disorders clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Defining the Rhythm: Developing a New Method to Describe Tremor and Myoclonus.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  5. Article
  6. Article
  7. Clinical and kinematic characterization of parkinsonian soft signs in essential tremor.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. The Italian tremor Network (TITAN): rationale, design and preliminary findings.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  14. Essential tremor plus rest tremor: current concepts and controversies.Journal of neural transmission (Vienna, Austria : 1996) · 2022
    Review
  15. Review
  16. Bayesian Interpretation of Essential Tremor Plus.Journal of clinical neurology (Seoul, Korea) · 2022
    Review
  17. Article
  18. Article
  19. Soft Signs in Essential Tremor Plus: A Prospective Study.Movement disorders clinical practice · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jos BecktepeDepartment of Neurology University Hospital Schleswig-Holstein, Christian-Albrechts-University Kiel Germany.
Felix GövertDepartment of Neurology University Hospital Schleswig-Holstein, Christian-Albrechts-University Kiel Germany.
Bettina BalintDepartment of Clinical and Movement Neurosciences, Queen Square Institute of Neurology University College London London UK.
Christian SchlenstedtDepartment of Neurology University Hospital Schleswig-Holstein, Christian-Albrechts-University Kiel Germany.
Kailash BhatiaDepartment of Clinical and Movement Neurosciences, Queen Square Institute of Neurology University College London London UK.ORCID https://orcid.org/0000-0001-8185-286X
Rodger ElbleDepartment of Neurology Southern Illinois University School of Medicine Springfield Illinois USA.
Günther DeuschlDepartment of Neurology University Hospital Schleswig-Holstein, Christian-Albrechts-University Kiel Germany.ORCID https://orcid.org/0000-0002-4176-9196

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with upper limb action tremor frequently exhibit additional neurological signs of uncertain significance. Clinicians vary in their interpretation, and interrater agreement on the final diagnosis is poor.

objectivesA new clinical tool for assessing the presence or absence of clinical signs that are important in axis-1 classification of tremor patients is introduced: the Standardized Tremor Elements Assessment (STEA). Interrater agreement is determined, and signs leading to disagreement in the final diagnosis are identified.

methodsThree tremor-focussed and one dystonia-focussed movement disorder specialists rated 59 videos of patients with upper limb action tremor syndromes using STEA. Interrater agreements for final diagnosis and STEA items were calculated.

resultsInterrater agreement regarding the final diagnosis was higher within the group of tremor specialists and poor between dystonia and tremor specialists. Greater agreement was found for items characterizing tremor than for signs of dystonia.

conclusionsClinical signs leading to diagnostic disagreement were identified with STEA, and STEA should therefore be useful in future studies of diagnostic disagreement. The thresholds for considering neurological signs as soft versus significant for ataxia, parkinsonism, dystonia, etc. are critically important in tremor classification and must be studied across movement disorder subspecialties, not simply within a pool of tremor specialists.

Indexed as

dystonic tremoressential tremortremortremor classification

Identifiers

PMID33816665
PMCPMC8015892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.