Evidence map›Paper›PMID 33816448›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Engineering a Human Pluripotent Stem Cell-Based

Nan Chen, Mieradilijiang Abudupataer, Sisi Feng, Shichao Zhu, Wenrui Ma, Jun Li, Hao Lai, Kai Zhu, Chunsheng Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Frontiers in bioengineering and biotechnology · 2026
    Review
  2. Vessel-On-A-Chip Coupled Proteomics Reveal Pressure-Overload-Induced Vascular Remodeling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  3. Review
  4. Review
  5. Mechanosignals in abdominal aortic aneurysms.Frontiers in cardiovascular medicine · 2022
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Nan ChenDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Mieradilijiang AbudupataerDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Sisi FengState Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Shichao ZhuDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Wenrui MaDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Jun LiDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Hao LaiDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Kai ZhuDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Chunsheng WangDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Fudan University · CNZhongshan Hospital · CNShanghai Institute of Hematology · CNSun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aortic aneurysm is a common cardiovascular disease characterised by continuous dilation of the aorta, and this disease places a heavy burden on healthcare worldwide. Few drugs have been suggested to be effective in controlling the progression of aortic aneurysms. Preclinical drug responses from traditional cell culture and animals are usually controversial. An effective

Indexed as

aortic aneurysmdrug screeninghuman pluripotent stem cellsmetforminmicrophysiological system

Identifiers

PMID33816448
PMCPMC8017487
OpenAlexW3139474153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.