ReviewFrontiers in pediatrics2021
Laboratory Markers in the Management of Pediatric Polytrauma: Current Role and Areas of Future Research.
Review in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed.
- Nonoperative Management of Pediatric Liver Injury: Current Evidence, Clinical Indications, and Outcomes.Medicina (Kaunas, Lithuania) · 2026Review
- Longitudinal Myocardial Deformation as an Emerging Biomarker for Post-Traumatic Cardiac Dysfunction.Life (Basel, Switzerland) · 2025Review
- Lactate Levels in a Replanted Limb as an Early Biomarker for Assessing Post-Surgical Evolution: A Case Report.Diagnostics (Basel, Switzerland) · 2025Article
- The Diagnosis and Management of Pediatric Blunt Abdominal Trauma-A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2024Review
- Bicarbonate and Serum Lab Markers as Predictors of Mortality in the Trauma Patient.The western journal of emergency medicine · 2024Article
- Pathophysiological changes and injury markers for acute lung injury from blunt impact in infant rabbits.Frontiers in pediatrics · 2024Article
- Article
- Whole-Body Magnetic Resonance Tomography and Whole-Body Computed Tomography in Pediatric Polytrauma Diagnostics-A Retrospective Long-Term Two-Center Study.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe trauma is the most common cause of mortality in children and is associated with a high socioeconomic burden. The most frequently injured organs in children are the head and thorax, followed by the extremities and by abdominal injuries. The efficient and early assessment and management of these injuries is essential to improve patients' outcome. Physical examination as well as imaging techniques like ultrasound, X-ray and computer tomography are crucial for a valid early diagnosis. Furthermore, laboratory analyses constitute additional helpful tools for the detection and monitoring of pediatric injuries. Specific inflammatory markers correlate with post-traumatic complications, including the development of multiple organ failure. Other laboratory parameters, including lactate concentration, coagulation parameters and markers of organ injury, represent further clinical tools to identify trauma-induced disorders. In this review, we outline and evaluate specific biomarkers for inflammation, acid-base balance, blood coagulation and organ damage following pediatric polytrauma. The early use of relevant laboratory markers may assist decision making on imaging tools, thus contributing to minimize radiation-induced long-term consequences, while improving the outcome of children with multiple trauma.
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Registered trials
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