Evidence map›Paper›PMID 33816214›Full record

ArticleFrontiers in oncology2020

Molecular Subtypes and CD4

Zhi-Kun Ning, Ce-Gui Hu, Chao Huang, Jiang Liu, Tai-Cheng Zhou, Zhen Zong

Abstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  8. Review
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  19. Article
  20. Potential ofOncoimmunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhi-Kun NingDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Ce-Gui HuDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Chao HuangDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Jiang LiuDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Tai-Cheng ZhouDepartment of Gastroenterological Surgery and Hernia Center, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangdong institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangzhou, China.
Zhen ZongDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCD4

methodsThree datasets obtained from microarray and the corresponding clinical data of GC patients were retrieved and downloaded from the Gene Expression Omnibus (GEO) database. We uploaded the normalize gene expression data with standard annotation to the CIBERSORT web portal for evaluating the proportion of immune cells in the GC samples. The WGCNA was performed to identify the modules the CD4

resultWe observed that a high abundance of CD4

conclusionWe identified three molecule subtypes, ten CD4

Indexed as

CD4+ memory T cellgastric cancerprognostic signaturetumor microenvironmentweighted gene co-expression network analysis

Identifiers

PMID33816214
PMCPMC8011500

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.