Evidence map›Paper›PMID 33816154›Full record

ArticleWorld journal of nephrology2021

Siblings with coronavirus disease 2019 infection and opposite outcome-the hemodialysis's better outcome paradox: Two case reports.

Dimitra Bacharaki, Evangelia Chrysanthopoulou, Sotiria Grigoropoulou, Panagiotis Giannakopoulos, Panagiotis Simitsis, Frantzeska Frantzeskaki, Aikaterini Flevari, Minas Karagiannis, Aggeliki Sardeli, Dimitra Kavatha and 2 more

Abstract readCase Reports
In one paragraph

Article in World journal of nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dimitra BacharakiDepartment of Nephrology, B Propaideutiki Internal Medicine Clinic, Attikon University Hospital, Chaidari 12064, Greece. bacharaki@gmail.com.
Evangelia ChrysanthopoulouIntensive Care Unit, Attikon University Hospital, Chaidari 12064, Greece.
Sotiria GrigoropoulouD Internal Medicine Clinic, Attikon University Hospital, Chaidari 12064, Greece.
Panagiotis GiannakopoulosDepartment of Nephrology, B Propaideutiki Internal Medicine Clinic, Attikon University Hospital, Chaidari 12064, Greece.
Panagiotis SimitsisIntensive Care Unit, Attikon University Hospital, Chaidari 12064, Greece.
Frantzeska FrantzeskakiIntensive Care Unit, Attikon University Hospital, Chaidari 12064, Greece.
Aikaterini FlevariIntensive Care Unit, Attikon University Hospital, Chaidari 12064, Greece.
Minas KaragiannisDepartment of Nephrology, B Propaideutiki Internal Medicine Clinic, Attikon University Hospital, Chaidari 12064, Greece.
Aggeliki SardeliDepartment of Nephrology, B Propaideutiki Internal Medicine Clinic, Attikon University Hospital, Chaidari 12064, Greece.
Dimitra KavathaD Internal Medicine Clinic, Attikon University Hospital, Chaidari 12064, Greece.
Anastasia AntoniadouD Internal Medicine Clinic, Attikon University Hospital, Chaidari 12064, Greece.
Demetrios VlahakosDepartment of Nephrology, B Propaideutiki Internal Medicine Clinic, Attikon University Hospital, Chaidari 12064, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) is a highly contagious infection caused by the severe acute respiratory syndrome coronavirus 2 virus and has a unique underlying pathogenesis. Hemodialysis (HD) patients experience high risk of contamination with COVID-19 and are considered to have higher mortality rates than the general population by most but not all clinical series. We aim to highlight the peculiarities in the immune state of HD patients, who seem to have both immune-activation and immune-depression affecting their outcome in COVID-19 infection. CASE SUMMARY: We report the opposite clinical outcomes (nearly asymptomatic course

conclusionThese cases may shed light on aspects of the immune responses to COVID-19 between HD and non-HD patients and stimulate further research in pathophysiology and treatment of this dreadful disease.

Indexed as

Case reportCOVID-19HemodialysisHost responseImmune-activationImmune-depressionSiblings

Identifiers

PMID33816154
PMCPMC8008982

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.