ReviewWorld journal of orthopedics2021
Dual antibiotic loaded bone cement in patients at high infection risks in arthroplasty: Rationale of use for prophylaxis and scientific evidence.
Review in World journal of orthopedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Sustained elution of amikacin, clindamycin, and vancomycin from a biodegradable cross-linked dextran gel.Scientific reports · 2026Article
- Small-colony variants of Staphylococcus aureus: hidden threat in chronic and recurrent infections.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Clinical outcomes of tibial cortex transverse transport versus antibiotic-loaded bone cement for Wagner grade 3-4 diabetic foot ulcers: a real-world retrospective cohort study.Frontiers in endocrinology · 2026Article
- Efficacy of Dual-Antibiotic-Loaded Bone Cement Against Multi-Drug-ResistantAntibiotics (Basel, Switzerland) · 2025Article
- Revision of unicondylar knee arthroplasty: an analysis of failure rates and contributing factors.Knee surgery & related research · 2025Article
- Review
- Gentamicin and clindamycin antibiotic-eluting depot technology eradicatesAntimicrobial agents and chemotherapy · 2024Article
- Article
- Development of aAntibiotics (Basel, Switzerland) · 2024Article
- Antibiotic-Loaded Ultrahigh Molecular Weight Polyethylenes.Macromolecular bioscience · 2024Article
- Case Report: Hip arthroplasty after fracture-related joint infection caused by extensively drug-resistantFrontiers in surgery · 2024Article
- Antibiotic bone cement combined with vacuum sealing drainage effectively repairs sacrococcygeal pressure ulcer.American journal of translational research · 2024Article
- A Low Rate of Periprosthetic Infections after Aseptic Knee Prosthesis Revision Using Dual-Antibiotic-Impregnated Bone Cement.Antibiotics (Basel, Switzerland) · 2023Article
- The Prophylactic Effect of Single vs. Dual Antibiotic-Loaded Bone Cement against Periprosthetic Joint Infection Following Hip Arthroplasty for Femoral Neck Fracture: An Analysis of the German Arthroplasty Registry.Antibiotics (Basel, Switzerland) · 2023Article
- Effect of the Antimicrobial Agents Peppermint Essential Oil and Silver Nanoparticles on Bone Cement Properties.Biomimetics (Basel, Switzerland) · 2022Article
- Patients at a high risk of PJI: Can we reduce the incidence of infection using dual antibiotic-loaded bone cement?Arthroplasty (London, England) · 2022Review
- [Research progress of antibacterial modification of orthopaedic implants surface].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2022Article
- Prophylactic Antibiofilm Activity of Antibiotic-Loaded Bone Cements against Gram-Negative Bacteria.Antibiotics (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In view of the demographic changes and projected increase of arthroplasty procedures worldwide, the number of prosthetic joint infection cases will naturally grow. Therefore, in order to counteract this trend more rigid rules and a stricter implementation of effective preventive strategies is of highest importance. In the absence of a "miracle weapon" priorities should lie in evidence-based measures including preoperative optimization of patients at higher infection risks, the fulfilment of strict hygiene rules in the operating theatre and an effective antibiotic prophylaxis regimen. Instead of a "one size fits all" philosophy, it has been proposed to adjust the antibiotic prophylaxis protocol to major infection risks taking into account important patient- and procedure-related risk factors. A stronger focus on the local application mode
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.