Evidence map›Paper›PMID 33816071›Full record

ArticleBalkan journal of medical genetics : BJMG2020

Influence of Potential Gene Polymorphisms on Propofol Dosage Regimen in Patients Undergoing Abdominal Hysterectomy.

E Ivanov, Z Sterjev, I Budic, J Nojkov, D Karadzova, A Sivevski

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Balkan journal of medical genetics : BJMG, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

E IvanovUniversity Clinic for Gynecology and Obstetrics, University "Ss Cyril and Methodius" Medical Faculty, Skopje, Republic of North Macedonia.
Z SterjevFaculty of Pharmacy, University "Ss Cyril and Methodius," Skopje, Republic of North Macedonia.
I BudicDepartment of Surgery and Anesthesiology, Medical Faculty, University of Nis, Nis Serbia.
J NojkovDepartment of Anesthesiology, University "Goce Delcev," Stip, Republic of North Macedonia.
D KaradzovaUniversity Clinic for Gynecology and Obstetrics, University "Ss Cyril and Methodius" Medical Faculty, Skopje, Republic of North Macedonia.
A SivevskiUniversity Clinic for Gynecology and Obstetrics, University "Ss Cyril and Methodius" Medical Faculty, Skopje, Republic of North Macedonia.
Saints Cyril and Methodius University of Skopje · MKGoce Delcev University · MKUniversity of Nis · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Propofol (2,6-diisopropylphenol) is the most common intravenous anesthetic used in modern medicine. It is postulated that individual differences in genetic factors [polymorphism of single nucleotide polymorphisms (SNPs)] in the genes encoding metabolic enzymes, molecular targets and molecular binding sites of propofol can be responsible for susceptibility to propofol effects. The aim of our study was to investigate the influence of the cytochrome P450 2B6 isozyme

Indexed as

ABCB1 geneCYP2B6 geneGABRA1 genePharmacogeneticPropofol

Identifiers

PMID33816071
PMCPMC8009561
OpenAlexW3143081064

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.