ArticleAmerican journal of cardiovascular disease2021
Opium Addiction and Correlation with Early and Six-month Outcomes of Presenting with ST Elevation Myocardial Infarction Treated Initially with Thrombolytic Therapy.
Article in American journal of cardiovascular disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Angiographic and early in-hospital profile of primary percutaneous coronary intervention in patients with substance use disorder presenting with ST-segment elevation myocardial infarction.Scientific reports · 2026Observational
- Opium Addiction and Coagulation Factors in ST-Segment Elevation Myocardial Infarction (STEMI) Patients: Implications for Thrombosis and Cardiovascular Outcomes.Iranian journal of public health · 2025Article
- How Does Opium Dependency Affect the Myocardial Infarction Outcomes? :.Galen medical journal · 2025Article
- Effects of opium use on one-year major adverse cardiovascular events (MACE) in the patients with ST-segment elevation MI undergoing primary PCI: a propensity score matched - machine learning based study.BMC complementary medicine and therapies · 2023Article
- Does Opioid Addiction Influence Clinical and Angiographic Outcomes in STEMI Patients Undergoing Emergency PCI?Advanced biomedical research · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMyocardial infarction is one of the most important causes of mortality worldwide. The role of opium addiction in the outcome of myocardial infarction is not known with many unproven beliefs surrounding it. This study was designed to evaluate the effects of opium addiction on in-hospital and six-month outcomes of patients presenting with ST elevation myocardial infarction (STEMI).
methodsThis study was performed on STEMI patients who were initially treated medically in two hospitals without any primary percutaneous coronary intervention (PCI) facility. A total 117 opium addicted patients and 217 non-opium-addicted controls were followed during hospitalization and six months thereafter. The primary endpoint of this study was the in-hospital composite of death, heart failure, recurrent chest pain, and recurrent STEMI.
resultsThe composite endpoint was not significantly different either in-hospital or after six-month follow up (RR=0.851, 95% CI: 0.578-1.253 and RR=0.899, 95% CI: 0.578-1.253 relatively). Multivariate analysis also confirmed that opium addiction was not a predictor of in-hospital or six-month adverse outcome.
conclusionThe present study revealed that in-hospital and six-month adverse outcomes in opium addicted patients presenting with STEMI were not significantly different in comparison to patients without any opium addiction.
Indexed as
Identifiers
33815927PMC8012279What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.