ReviewAging and disease2021
Obstructive Sleep Apnea-hypopnea Syndrome as a Novel Potential Risk for Aging.
Review in Aging and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Association between obstructive sleep apnea syndrome and metabolic syndrome: a severity-stratified meta-analysis.Frontiers in medicine · 2026Pooled it
- Association of accelerated biological aging with obstructive sleep apnea symptoms and identification of a candidate biomarker gene signature.Clinical epigenetics · 2026Article
- Multi night digital assessment of sleep disordered breathing is associated with accelerated vascular aging.NPJ digital medicine · 2026Article
- Unveiling the role of EGR1 and hub senescence-related genes in type II alveolar epithelial cells senescence for obstructive sleep apnea.BMC biotechnology · 2025Article
- Association between pollinosis and obstructive sleep apnea hypopnea syndrome in the US population: evidence from the NHANES database 2005-2018.BMC pulmonary medicine · 2025Article
- Sleep traits causally affect epigenetic age acceleration: a Mendelian randomization study.Scientific reports · 2025Article
- Unraveling the interplay between sleep, redox metabolism, and aging: implications for brain health and longevity.Frontiers in aging · 2025Review
- Delayed medical consultation and influencing factors in elderly patients with obstructive sleep apnea syndrome.Frontiers in medicine · 2025Article
- Cardiac structural and functional changes in OSAHS patients with heart failure with preserved ejection fraction and atrial fibrillation.BMC cardiovascular disorders · 2024Article
- Correlation between the gut microbiome and neurodegenerative diseases: a review of metagenomics evidence.Neural regeneration research · 2024Review
- Unraveling the Complexities of Oxidative Stress and Inflammation Biomarkers in Obstructive Sleep Apnea Syndrome: A Comprehensive Review.Life (Basel, Switzerland) · 2024Review
- Intermittent hypoxia induces hepatic senescence through promoting oxidative stress in a mouse model.Sleep & breathing = Schlaf & Atmung · 2024Article
- The common link between sleep apnea syndrome and osteoarthritis: a literature review.Frontiers in medicine · 2024Review
- Exploring the role of aging in the relationship between obstructive sleep apnea syndrome and osteoarthritis: Insights from NHANES data.Frontiers in medicine · 2024Article
- Danggui-Buxue decoction alleviated vascular senescence in mice exposed to chronic intermittent hypoxia through activating the Nrf2/HO-1 pathway.Pharmaceutical biology · 2023Article
- Wavelet Analysis of Respiratory Muscle sEMG Signals during the Physiological Breakpoint of Static Dry End-Expiratory Breath-Holding in Naive Apneists: A Pilot Study.Sensors (Basel, Switzerland) · 2023Article
- [Research Status of and Recommendations for Prevention and Control of Sleep Disorders in China].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023Review
- Body weight and obstructive sleep apnea: a mathematical relationship between body mass index and apnea-hypopnea index in veterans.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Effects of Obstructive Sleep Apnea-Hypopnea Syndrome and Cognitive Function in Ischemic Stroke Based on Linear Regression Equation.Scanning · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a common sleep disorder, negatively influencing individuals' quality of life and socioeconomic burden. In recent years, OSAHS has been reported in not only constituting an aging-associated disease, but also in accelerating and/or potentiating aging mechanisms. However, the negative impacts of OSAHS on aging are underestimated because of low level of public awareness about this disease and high rates of undiagnosed cases, which are more critical in developing countries or economically disadvantaged regions. Hence, reviewing previously reported observations may assist scholars to better indicate that OSAHS is likely a novel potential risk for aging. Further understanding of the pathophysiological mechanism of OSAHS and its role in procession of aging may markedly highlight the importance of this common sleep disorder.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.