Evidence map›Paper›PMID 33815780›Full record

ReviewClinical kidney journal2021

Kidney transplantation and COVID-19 renal and patient prognosis.

Néstor Toapanta, Irina B Torres, Joana Sellarés, Betty Chamoun, Daniel Serón, Francesc Moreso

Open access · goldAbstract readReview
In one paragraph

Review in Clinical kidney journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Severe COVID-19 in 2 Kidney Transplant Patients in Gabon.The American journal of case reports · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Farewell from theClinical kidney journal · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Weak antibody response to three doses of mRNA vaccine in kidney transplant recipients treated with belatacept.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Néstor ToapantaDepartment of Nephrology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Irina B TorresDepartment of Nephrology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Joana SellarésDepartment of Nephrology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Betty ChamounDepartment of Nephrology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Daniel SerónDepartment of Nephrology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Francesc MoresoDepartment of Nephrology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Vall d'Hebron Hospital Universitari · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVD-19) emerged as a pandemic in December 2019. Infection has spread quickly and renal transplant recipients receiving chronic immunosuppression have been considered a population at high risk of infection, complications and infection-related death. During this year a large amount of information from nationwide registries, multicentre and single-centre studies have been reported. The number of renal transplant patients diagnosed with COVID-19 was higher than in the general population, but the lower threshold for testing may have contributed to its better identification. Major complications such as acute kidney injury and acute respiratory distress syndrome were very frequent in renal transplant patients, with a high comorbidity burden, but further studies are needed to support that organ transplant recipients receiving chronic immunosuppression are more prone to develop these complications than the general population. Kidney transplant recipients experience a high mortality rate compared with the general population, especially during the very early post-transplant period. Despite the fact that some studies report more favourable outcomes in patients with a kidney transplant than in patients on the kidney waiting list, the higher mortality described in the very early post-transplant period would advise against performing a kidney transplant in areas where the spread of infection is high, especially in recipients >60 years of age. Management of transplant recipients has been challenging for clinicians and strategies such as less use of lymphocyte-depleting agents for new transplants or anti-metabolite withdrawal and calcineurin inhibitor reduction for transplant patients with COVID-19 are not based on high-quality evidence.

Indexed as

acute kidney injuryacute respiratory distress syndromeCOVID-19mortalityrenal transplantationSARS-CoV-2

Identifiers

PMID33815780
PMCPMC7995521
OpenAlexW3143060041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.